1925: Dr. Robert E. Swain, Stanford University professor of chemistry, champions the idea of an interdisciplinary research institute within the University. Early supporters include Stanford alumnus and trustee, Herbert Hoover, the 31st U.S. President.

1929: Stanford's annual report presents a faculty proposal for a research institute.

1939: Stanford's faculty committee discusses the institute idea while meeting at the Bohemian Grove in Northern California. Stanford President Ray Lyman Wilbur presents the idea to University trustees.