The objective of pharmaceutical science is to develop a product with the therapeutic amount of drug in the right form, and to maintain its chemical and biological integrity for delivery at the proper time and rate at the desired site. SRI’s Pharmaceutical Sciences group has decades of experience, including:

• Preparation of dose formulations for preclinical in vitro and in vivo safety studies
• Design and manufacture of finished drug product dosage forms for clinical trials

Our specialized drug delivery approaches can improve efficacy and safety as well as patient convenience and compliance. The group applies its extensive expertise to improving drug candidates of low solubility, low bioavailability, short half-life, poor stability, or gastric intolerability. Our analytical chemists develop and apply sensitive, selective, and robust methods for establishing the identity, strength, quality, purity, and stability of active ingredients and drug products.

A wide range of chromatography, spectroscopy, and product testing techniques are available to support R&D and FDA-regulated Good Laboratory Practice (GLP) and current Good Manufacturing Process (cGMP) studies. Method development and validation, pharmaceutical analysis, quality control, and stability studies are performed on a standalone basis or as part of an integrated drug development program from Idea to IND®.

In 2012, the Pharmaceutical Sciences team was selected for an SRI Presidential Achievement Award for its contributions.