Adolf Pfefferbaum

Adolf Pfefferbaum, director of the Neuroscience Program in the Center for Health Sciences at SRI International, has been at the forefront of neuroimaging and electrophysiological research in normal aging and neuropsychiatric disorders for more than three decades. At SRI, he has focused on devising novel approaches for quantitative neuroimaging data to yield measures of brain structures and tissue composition (using magnetic resonance imaging, MRI), microstructure (MR diffusion tensor imaging, DTI), chemistry (magnetic resonance spectroscopy), and function (functional MRI) in the living human.

Pfefferbaum’s research in chronic alcoholism has enabled detection of alcoholism's dynamic course, through drinking, sobriety, and relapse, and has demonstrated an increased vulnerability of the aging brain to excessive drinking. Recently, he has implemented neuroimaging methods to parallel human conditions in animal models to identify mechanisms of harm with drinking and healing with sobriety.

In 2011, the Research Society on Alcoholism selected Pfefferbaum for its Distinguished Researcher Award. Pfefferbaum was named an SRI Fellow in 2007.