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In Vivo Assessment of Pain

SRI currently offers in vivo models for both acute and chronic pain.

Acute Pain

Acute models include:

  • Tail flick test
  • Formalin test
  • Carageenan-induced inflammation/hyperalgesia

Chronic Pain


Chronic pain models include:

  • Complete Freund's adjuvant-induced arthritis
  • Peripheral mononeuropathy (Bennett model)*
  • Diabetic neuropathy (streptozotocin model)*

*Von Frey test and/or paw withdrawal are used to assess allodynia.


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       Last Updated Jul 17, 2008

 

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