In Vitro Assessment of Inflammation

Whether you need to evaluate a compound for its ability to inhibit an enzyme or the effects it has on immune response, SRI can help. We have state-of-the-art resources for analytical and functional immunology studies. Our receptor pharmacologists have extensive expertise in assay development.

Immunology Services

Flow Cytometry Services

• Ca²⁺ flux analysis
• Cell cycle and kinetic analysis
• Multivariate (three- and four-color) surface and cytoplasmic immunophenotyping

In Vitro Bioassays

• Natural killer (NK) cell Assays
• Cytotoxic T lymphocyte assays
• Antigen-specific functional lymphoproliferative assays
• Mixed lymphocyte cultures
• Cytokine assays (ELISA and intracellular flow cytometric analysis)
• Single cell cytokine assays (ELISPOT)
• Immunoblotting technologies
• Antigen uptake, processing and presentation
• Viral assays
• Large-scale humanlymphocyte activation

Receptor Pharmacology

We work with clients to develop and implement the receptor-based assays they need to evaluate their compounds. We specialize in the

• Development of novel assays for receptor ligand binding and enzyme inhibition
• Improvement of existing assay techniques
• Automation of assays for medium to high throughput.

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       Last Updated Jul 17, 2008