Therapeutic Areas

SRI Biosciences can meet all of your preclinical needs from lead identification to Phase I clinical trials, in timeframes well below industry averages. SRI's integrated program offers immunology, pathology, neuropharmacology, molecular biology, medicinal chemistry, pharmacology, toxicology, engineering, and information technology expertise to solve problems and create value. Our comprehensive drug development capabilities, including IND preparation for filing, are designed to expedite the preclinical process. All of our services are performed at one location.

We provide services in the following therapeutic areas. Click on each one for more information:

Cancer Therapeutics
SRI, a long-time NCI contractor, is a leading provider of preclinical development services for cancer therapeutics, cancer vaccines, and chemopreventive agents. For government and private clients, we identify new molecular targets, discover novel lead compounds, develop new models for evaluating in vitro and in vivo efficacy, elucidate mechanisms of action, optimize interesting leads, and develop cost-effective syntheses.

Infectious Disease
SRI is the world's leading provider of preclinical development services for anti-infective therapeutics and vaccines. A leader in performing antimicrobial assays with novel agents, we offer discovery services in lead compound discovery and optimization, in vitro and in vivo model development, mechanisms of action elucidation, and cost-effective synthesis development.

Inflammation
SRI provides a variety of in vitro immunology services applicable to the immune system’s response to injury and chronic inflammation. We evaluate the in vivo effectiveness of anti-inflammatory agents using well-established animal models.

Pain/Analgesia
Our neuropharmacology group assists clients by evaluating their compounds for pain/analgesia and other neurological disorders using isolated receptors and functional assays. We evaluate the in vivo effectiveness of agents using well-established animal models.

Sleep
We are currently studying the relationship between the hypocretin/orexin (H/O) system and sleep disorders and using differential gene expression approaches including microarrays to identify other components of the sleep/wake regulatory network. Discovering the molecular bases for sleep disorders could lead to improved treatments for insomnia, shift work/jet lag, age-related sleep disturbances, fatigue, and narcolepsy. We provide clients a number of neurobiology services, including in vitro and in vivo electrophysiology, receptor assays, and neuroanatomy. We evaluate the in vivo effects of agents in our dedicated Sleep and Circadian Rhythm Animal Facility.

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       Last Updated Jun 15, 2006