Metabolic Diseases

Metabolic diseases such as diabetes and obesity occur when abnormal chemical reactions disrupt the hormonal regulation of the body's absorption and utilization of food. To find treatments, diabetes research and obesity research are ongoing. Researchers at SRI's Center for Advanced Drug Research engage in metabolic disease research to develop novel molecules to control hormonal regulation.

Using bioinformatics tools, SRI researchers also study the chemical reaction pathways of metabolism. MetaCyc, from the SRI BioCyc database collection, is the largest database of experimentally determined and literature-curated metabolic pathways currently available to the metabolism research community.

Projects

silhouette of a man looking at BioCyc software
BioCyc Database Collection

A comprehensive website for sharing fundamental information about biochemical pathways and genomes with researchers around the world.

Topics: Artificial Intelligence Bioinformatics + Computational Biology Drug Discovery Metabolic Diseases
twin boys
Twin Research Registry at SRI International

SRI established the Twin Research Registry as part of its scientific research and efforts to discover more about human behavior. Fraternal and identical twins and multiples of all ages are invited to join the Registry for consideration for research studies.

Topics: Addiction Research Aging Research Behavioral Health Disease Focus Areas Human Sleep Metabolic Diseases Neurodegenerative Diseases Neuroscience Sleep Disorders Twins Research

Press Releases

Joseph Rogers
Joseph Rogers Joins SRI International as Executive Director of New Health Sciences Section in Biosciences Division

In his career, Rogers has focused on age-related neurologic diseases. He is best known for showing that inflammatory responses occur in almost all major age-related brain disorders and cause substantial damage, with his seminal paper in the area receiving nearly 1,200 citations to date.

Topics: Addiction Research Aging Research Behavioral Health Biomarkers Human Sleep Metabolic Diseases Neurodegenerative Diseases Neuroscience
researchers in SRI lab
SRI International Awarded Contract Worth Up to $100M from National Institute of Allergy and Infectious Diseases

SRI International has been awarded a contract worth up to $100.5 million over 10 years from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH)

Topics: Disease Focus Areas Drug Discovery Immunology + Inflammation Infectious Diseases Metabolic Diseases Microbiology Pharmaceutical R+D Pre-formulation Studies Preclinical Drug Development Target Validation + Assay Development Vaccine Development

Divisions, Centers + Labs