Synthetic Biology

A novel area of research at the intersection of biology and engineering, synthetic biology includes design and construction of new biological parts, devices, and systems, and redesign of existing natural biological systems for useful purposes.

To develop new methods for combating diseases such as cancer and problems associated with aging and sleep disorders, SRI conducts collaborative research in synthetic biology, symbolic systems biology, computational biology, and bioinformatics. We advance scientific understanding of biological systems to accelerate drug discovery and development.

We also seek to understand how the pathways of cell biology can be modeled with the same tools used to model computer circuits, and create logic machines by integrating components into higher-order genetic networks using mathematical modeling.

Press Releases

two silhouetted figures look at computer screens

Agilent Technologies Inc. and SRI have signed a licensing agreement to offer laboratory research customers an integrated package that includes SRI's complete BioCyc Pathway Database Collection.

Collaborative Drug Discovery, Inc. and SRI International have been awarded a second National Institute of Allergy and Infectious Diseases (NIAID) grant to continue development of an information repository and software to identify novel therapeutics for tuberculosis.

complete human metabolic pathway map

A new software tool can substantially decrease time required for researchers to construct genome-scale models of metabolic networks. Metabolic networks are the complete set of metabolic and physical processes that determine physiological and biochemical properties of a cell.

SRI In the News

TB Drug Discovery

This article reports that Collaborative Drug Discovery (CDD) and SRI International won a second Phase II Small Business Technology Transfer Research (STTR) grant to support the continued development of a computational approach to tuberculosis (TB) drug discovery.