Projects

Center for Health Sciences

scientist with a computer model of a molecular structure
Bis-Indole Drug Discovery in Multiple Therapeutic Areas

SRI is identifying candidates for advanced therapies in multiple disease areas by developing compounds from synthetically optimized, natural dietary products.
nicotinic receptors affect brain activity
Role of Alpha6 Nicotinic Receptors in Smoking

To support more effective cessation treatments, SRI researchers are exploring how nicotinic receptors affect brain activity in response to smoking.
diagram of nicotinic receptors
Role of Nicotinic Receptors in Parkinson’s Disease

SRI is investigating whether the nicotine in tobacco smoke may be useful in meeting the urgent need to manage Parkinson’s disease.
Salivary Biomarkers, Life Stress + Nicotine Dependence

Predicting individuals' vulnerability to nicotine dependence could identify factors in genes and the environment that help to explain the success or failure of attempts to prevent tobacco use and addiction.
middle-aged woman relaxing on bed
Sleep and Reproductive Transitions in Menopausal Women

Sleep complaints are common during the transition to menopause, yet we have little understanding of what drives this increase in sleep disturbance and how best to treat it. SRI researchers are investigating sleep quality in women who have begun to go through menopause.
cigarette being snapped in half
Treatment of Nicotine Dependence in a Healthcare Setting

SRI is analyzing the genetics of smoking and related characteristics, using data from a large-scale National Cancer Institute study on smoking cessation.
twin boys
Twin Research Registry at SRI International

SRI established the Twin Research Registry as part of its scientific research and efforts to discover more about human behavior. Fraternal and identical twins and multiples of all ages are invited to join the Registry for consideration for research studies.
Twins on bicycles
Using Twins to Understand Opioid Efficacy

SRI is studying twins to gain more clinical insight into physiologic response to powerful opioid painkillers. Study results should help to optimize pain relief and minimize adverse effects.
An SRI vaccine researcher in protective clothing and a mask
Vaccinations and Next-Generation Pandemic Respiratory Viruses

To help prepare for next-generation pandemics, SRI is partnering with Stanford University to examine vaccination responses.