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Director, General Toxicology, Preclinical Development
Toufan Parman, Ph.D., DABT, oversees a variety of toxicology testing programs. She is currently serving as the principal investigator on a National Cancer Institute (NCI) Toxicology and Pharmacology, NCI PREVENT, and NICHD Biological Testing Facility Contracts, co-investigator on three other National Institutes of Health contracts, and as a member of the Pharmacology and Toxicology Center on the NHLBI SMARTT Program Steering Committee.
Parman is an experienced toxicologist with broad technical proficiency in organic chemistry, neurotoxicology, molecular and cell biology, pharmacology, and reproductive and general toxicology. As a result, she has the ability to integrate molecular and cellular approaches to assess pharmacological outcomes and mechanism of action for various therapeutic molecules. Parman has a broad background in drug development and has designed, developed and implemented preclinical plans in support of IND/NDA submissions for various therapeutics such as small molecules drugs, vaccines, viruses, proteins/antibodies, and stem cell therapeutics.
Parman is an accomplished scientist who has produced seminal results and contributed both conceptually and technically to her fields of expertise, as demonstrated by her publications in journals such as Nature Medicine, FASEB Journal, Toxicological Sciences, and Drug Metabolism and Disposition. She has also authored several reviews, and book chapters. Parman has developed and filed a patent on a novel method for delivery of stem cells to the brain via the nasal passages.
Prior to joining SRI, Parman was a postdoctoral fellow at Stanford University, School of Medicine, Department of Hepatology and Gastroenterology where she studied the role of RACK 1 signaling in colon cancer.
Parman received her B.Sc. with honors in chemistry from Dalhousie University of Nova Scotia, Canada, M.Sc. in physical organic chemistry, and Ph.D. in pharmaceutical sciences from the University of Toronto, Canada. She has been certified by the American Board of Toxicology since 2007.