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Home » Archives for Srini Krishnamurthy
Srini Krishnamurthy

Srini Krishnamurthy

Senior Principal Scientist and Program manager, Security and Survivability
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Publications

Oceans & space publications October 1, 2016 Tech Report

Thermal insulator transition induced by interface scattering

Srini Krishnamurthy

We develop an effective medium model of thermal conductivity that accounts for both percolation and interface scattering. This model accurately explains the measured increase and decrease of thermal conductivity with loading in composites dominated by percolation and interface scattering, respectively. Our model further predicts that strong interface scattering leads to a sharp decrease in thermal conductivity, or an insulator transition, at high loadings when conduction through the matrix is restricted and heat is forced to diffuse through particles with large interface resistance. The accuracy of our model and its ability to predict transitions between insulating and conducting states suggest it can be a useful tool for designing materials with low or high thermal conductivity for a variety of applications.

Oceans & space publications April 1, 2014 Article

Experimental Demonstration of a Broadband All-Dielectric Metamaterial Perfect Reflector

SRI International, Srini Krishnamurthy

Here we present the demonstration of a single-negative all-dielectric metamaterial, comprised of a single layer of cylindrical silicon resonators on a silicon-on-insulator substrate, that possesses peak reflectance over[…]

Oceans & space publications April 1, 2014 Article

Fabrication of Highly Spin-Polarized Co2FeAl0.5Si0.5 Thin-Films

Srini Krishnamurthy

The sleep disorder narcolepsy results from loss of hypothalamic orexin/hypocretin neurons. Although narcolepsy onset is usually postpubertal, current mouse models involve loss of either orexin peptides or orexin neurons from birth. To create a model of orexin/hypocretin deficiency with closer fidelity to human narcolepsy, diphtheria toxin A (DTA) was expressed in orexin neurons under control of the Tet-off system. Upon doxycycline removal from the diet of postpubertal orexin-tTA;TetO DTA mice, orexin neurodegeneration was rapid, with 80% cell loss within 7 d, and resulted in disrupted sleep architecture. Cataplexy, the pathognomic symptom of narcolepsy, occurred by 14 d when ∼5% of the orexin neurons remained. Cataplexy frequency increased for at least 11 weeks after doxycycline. Temporary doxycycline removal followed by reintroduction after several days enabled partial lesion of orexin neurons. DTA-induced orexin neurodegeneration caused a body weight increase without a change in food consumption, mimicking metabolic aspects of human narcolepsy. Because the orexin/hypocretin system has been implicated in the control of metabolism and addiction as well as sleep/wake regulation, orexin-tTA; TetO DTA mice are a novel model in which to study these functions, for pharmacological studies of cataplexy, and to study network reorganization as orexin input is lost.

Oceans & space publications October 1, 2013 Article

Perfect Dielectric-Metamaterial Reflector

SRI International, Srini Krishnamurthy

We exploit the Mie resonance in dielectric microparticles to design a single-negative metamaterial monolayer with near-unity reflectivity and negligible absorptivity

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