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Toufan Parman

Senior Director, Toxicology and Immunology, Preclinical Development

Toufan Parman, Ph.D., DABT, is an accomplished toxicologist with more than 15 years of experience in the management and conduct of preclinical drug development projects for advancing various pharmaceutical products such as small molecule drugs, biologics, devices, and cell therapies.  Parman has designed, developed, and implemented preclinical drug development plans and has authored several sections of IND/NDA submissions for various therapeutics.  Parman has helped advance several drugs into clinical trials including two of the National Institutes of Child health and Human Development’s (NICHD’s) novel male contraceptives currently in clinical Phase I and II.  A large portion of her career has focused on development of antifertility, and anticancer therapies.

Parman has broad technical proficiency in organic chemistry, neurotoxicology, molecular and cell biology, pharmacology, and reproductive and general toxicology.  She has published extensively in her areas of expertise; she is the author of more than 60 publications, book chapters, and abstracts.

Parman oversees a variety of toxicology testing programs and immunology assay development.  She is currently serving as the principal investigator on several National Institutes of Health (NIH) drug development contracts.  In addition, she is responsible for management of several functional groups at SRI.  Parman is a member of the Critical Path Institute, Predictive Safety Testing Consortium (PSTC) where she is involved in development of translatable biomarkers of toxicity.  She has helped develop clinical biomarkers of cardiovascular toxicity and is currently involved in development of translatable biomarkers of testicular toxicity.  Parman has served as the K-12 outreach program coordinator, treasurer, and President of Northern California (NorCal) Chapter of the Society of Toxicology (SOT).  She is currently the past president of NorCal SOT and continues her active support of this regional chapter.

Parman served a postdoctoral fellow at the National Cancer Institute Laboratory of Cellular Oncology under the supervision of Dr. Douglas Lowy (Current Deputy Director of NCI and Chief of the Laboratory of Cellular Oncology) where she studied cell signaling and cancer.  Prior to joining SRI, Parman completed a second postdoctoral training at Stanford University, School of Medicine, Department of Hepatology and Gastroenterology where she studied the role of RACK 1 signaling in colon cancer under the supervision of Dr. Christina Cartwright.

Parman received her B.Sc. with honors in chemistry from Dalhousie University, Nova Scotia, Canada, M.Sc. in physical organic chemistry, and Ph.D. in pharmaceutical sciences from the University of Toronto, Canada.  She has been certified by the American Board of Toxicology since 2007.

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