{"id":93266,"date":"2024-09-26T19:00:00","date_gmt":"2024-09-26T23:00:00","guid":{"rendered":"https:\/\/www.sri.com\/?p=93266"},"modified":"2024-09-26T08:33:42","modified_gmt":"2024-09-26T12:33:42","slug":"n4-pharma%e3%81%a8%e3%81%ae%e5%85%b1%e5%90%8c%e7%a0%94%e7%a9%b6%e3%81%a7%e3%80%81%e3%81%93%e3%82%8c%e3%81%be%e3%81%a7%e5%88%b0%e9%81%94%e3%81%a7%e3%81%8d%e3%81%aa%e3%81%8b%e3%81%a3%e3%81%9f%e4%ba%ba","status":"publish","type":"post","link":"https:\/\/www.sri.com\/ja\/press\/story\/n4-pharma%e3%81%a8%e3%81%ae%e5%85%b1%e5%90%8c%e7%a0%94%e7%a9%b6%e3%81%a7%e3%80%81%e3%81%93%e3%82%8c%e3%81%be%e3%81%a7%e5%88%b0%e9%81%94%e3%81%a7%e3%81%8d%e3%81%aa%e3%81%8b%e3%81%a3%e3%81%9f%e4%ba%ba\/","title":{"rendered":"N4 Pharma\u3068\u306e\u5171\u540c\u7814\u7a76\u3067\u3001\u3053\u308c\u307e\u3067\u5230\u9054\u3067\u304d\u306a\u304b\u3063\u305f\u4eba\u4f53\u5185\u306e\u7d30\u80de\u3092\u6a19\u7684\u306b\u3059\u308b\u6cbb\u7642\u3092\u958b\u767a"},"content":{"rendered":"\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1920\" height=\"1080\" src=\"https:\/\/www.sri.com\/wp-content\/uploads\/2024\/05\/cancer-cells-1920.png\" alt=\"\" class=\"wp-image-89601\" srcset=\"https:\/\/www.sri.com\/wp-content\/uploads\/2024\/05\/cancer-cells-1920.png 1920w, https:\/\/www.sri.com\/wp-content\/uploads\/2024\/05\/cancer-cells-1920-300x169.png 300w, https:\/\/www.sri.com\/wp-content\/uploads\/2024\/05\/cancer-cells-1920-1024x576.png 1024w, https:\/\/www.sri.com\/wp-content\/uploads\/2024\/05\/cancer-cells-1920-768x432.png 768w, https:\/\/www.sri.com\/wp-content\/uploads\/2024\/05\/cancer-cells-1920-1536x864.png 1536w, https:\/\/www.sri.com\/wp-content\/uploads\/2024\/05\/cancer-cells-1920-500x281.png 500w, https:\/\/www.sri.com\/wp-content\/uploads\/2024\/05\/cancer-cells-1920-800x450.png 800w, https:\/\/www.sri.com\/wp-content\/uploads\/2024\/05\/cancer-cells-1920-1280x720.png 1280w\" sizes=\"auto, (max-width: 1920px) 100vw, 1920px\" \/><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-dashed-sep-1\"\/>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center\">\u6a19\u7684\u6cbb\u7642\u306e\u9053\u3092\u5207\u308a\u958b\u304f\u3053\u306e\u5171\u540c\u7814\u7a76\u306f\u3001\u30d7\u30ec\u30b7\u30b8\u30e7\u30f3\u30d8\u30eb\u30b9\u30b1\u30a2\u306e\u53ef\u80fd\u6027\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3059\u3053\u3068\u3092\u76ee\u6307\u3059<\/h2>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-dashed-sep-1\"\/>\n\n\n\n<p>\u5c02\u9580\u88fd\u85ac\u4f1a\u793e\u306eN4 Pharma\u306f\u3001\u304c\u3093\u6cbb\u7642\u3084\u30ef\u30af\u30c1\u30f3\u958b\u767a\u306b\u5bc4\u4e0e\u3059\u308b\u65b0\u305f\u306a\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u9001\u9054\u30b7\u30b9\u30c6\u30e0Nuvec\u00ae\u3092\u958b\u767a\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306eN4 Pharma\u3068SRI\u306f\u3001SRI\u304c\u72ec\u81ea\u306b\u958b\u767a\u3057\u305fFOX Three\u5206\u5b50\u8a98\u5c0e\u7d30\u80de\u6a19\u7684\u5316\u30b7\u30b9\u30c6\u30e0\uff08MGS\uff09\uff08FOX Three Molecular Guidance System\u2122\uff09\u3068Nuvec\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u5171\u540c\u7814\u7a76\u306b\u5411\u3051\u3066\u5951\u7d04\u3092\u7de0\u7d50\u3057\u307e\u3057\u305f\u3002\u4e21\u793e\u306f\u3053\u306e\u7d44\u307f\u5408\u308f\u305b\u305f\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u3092\u5171\u540c\u3067\u4e0a\u5e02\u3059\u308b\u3053\u3068\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e21\u793e\u306f\u3001\u7279\u5b9a\u306e\u7d30\u80de\u3078\u306e\u7d30\u80de\u5185\u9001\u9054\u3092\u9ad8\u3081\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u3001SRI\u306eMGS\u30b7\u30b9\u30c6\u30e0\u3068Nuvec\u3092\u7d71\u5408\u3055\u305b\u308b\u7814\u7a76\u3092\u5171\u540c\u3067\u5b9f\u65bd\u3057\u307e\u3059\u3002N4 Pharma\u3068SRI\u306f\u3001\u3053\u306e\u7d71\u5408\u3055\u305b\u305f\u6280\u8853\u3092\u57fa\u306b\u3057\u305f\u3001\u65b0\u305f\u306a\u4e8b\u696d\u306e\u6a5f\u4f1a\u3092\u958b\u62d3\u30fb\u8ffd\u6c42\u3057\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>SRI\u306eMGS\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u306f\u3001\u9ad8\u5206\u5b50\u30d0\u30a4\u30aa\u6cbb\u7642\u85ac\u306e\u7d30\u80de\u5185\u9001\u9054\u304c\u59a8\u3052\u3089\u308c\u3066\u3057\u307e\u3046\u3068\u3044\u3046\u969c\u58c1\u3092\u514b\u670d\u3059\u308b\u3088\u3046\u306b\u8a2d\u8a08\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u30b7\u30b9\u30c6\u30e0\u306f\u3001\u9ad8\u5206\u5b50\u306e\u30da\u30a4\u30ed\u30fc\u30c9\uff08\u6cbb\u7642\u6a19\u7684\u306b\u52b9\u304f\u85ac\u7269\uff09\u3092\u6a19\u7684\u7d30\u80de\u306b\u9001\u9054\u3057\u3001\u3055\u3089\u306b\u305d\u306e\u7d30\u80de\u5185\u306e\u7279\u5b9a\u306e\u5834\u6240\u3078\u306e\u9001\u9054\u3092\u3082\u53ef\u80fd\u306b\u3059\u308b\u72ec\u81ea\u306e\u6280\u8853\u3092\u63a1\u7528\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7cbe\u5bc6\u533b\u7642\uff08\u30d7\u30ec\u30b7\u30b8\u30e7\u30f3\u30e1\u30c7\u30a3\u30b7\u30f3\uff09\u306e\u30bf\u30fc\u30b2\u30c3\u30c8<\/h2>\n\n\n\n<p>SRI\u306eMGS\u306f\u3001\u6a5f\u80fd\u6027\u9175\u7d20\u3084\u6297\u4f53\u3001\u6838\u9178\uff08siRNA\u3001ASO\u3001DNA\u3092\u542b\u3080\uff09\u3001\u30ea\u30dd\u30bd\u30fc\u30e0\u3001\u30ca\u30ce\u7c92\u5b50\u306a\u306912\u7a2e\u3092\u8d85\u3048\u308b\u30da\u30a4\u30ed\u30fc\u30c9\u3092\u9001\u9054\u3067\u304d\u308b\u3053\u3068\u3001\u307e\u305f\u3001\u3053\u308c\u307e\u3067\u306f\u5230\u9054\u3067\u304d\u306a\u3044\u3053\u3068\u304b\u3089\u3001\u6cbb\u7642\u304c\u4e0d\u53ef\u80fd\u3067\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u305f\u7d30\u80de\u5185\u306e\u5206\u5b50\u6a19\u7684\u90e8\u4f4d\u306b\u9001\u9054\u3067\u304d\u308b\u3053\u3068\u3092\u5b9f\u8a3c\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-pullquote is-style-machina-pullquote has-large-font-size\"><blockquote><p>\u300c\u3053\u308c\u306f\u3001\u6cbb\u7642\u306e\u53ef\u80fd\u6027\u3092\u62e1\u5927\u3059\u308b\u3068\u3068\u3082\u306b\u3001\u751f\u7269\u533b\u5b66\u306e\u5c55\u671b\u3092\u5909\u3048\u308b\u524d\u9014\u6709\u671b\u306a\u65c5\u306e\u59cb\u307e\u308a\u3092\u610f\u5473\u3057\u307e\u3059\u300d\u2015Kathlynn Brown<\/p><\/blockquote><\/figure>\n\n\n\n<p>N4 Pharma\u306e\u30b7\u30ea\u30ab\u30ca\u30ce\u7c92\u5b50Nuvec\u306f\u4e0d\u898f\u5247\u306a\u8868\u9762\u69cb\u9020\u3092\u3057\u3066\u304a\u308a\u3001siRNA\u3001RNA\u3001DNA\u3092\u30b7\u30f3\u30d7\u30eb\u304b\u3064\u52b9\u679c\u7684\u306b\u6355\u6349\u30fb\u4fdd\u8b77\u3057\u3066\u7d30\u80de\u819c\u3078\u306e\u9001\u9054\u304c\u3067\u304d\u307e\u3059\u3002\u3044\u3063\u305f\u3093\u7d30\u80de\u5185\u306b\u5165\u308b\u3068\u3001\u3053\u306esiRNA\u3001RNA\u3001DNA\u306f\u653e\u51fa\u3055\u308c\u3066\u7d30\u80de\u306e\u6a5f\u69cb\u5185\u306b\u5165\u308a\u8fbc\u307f\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u30b5\u30a4\u30ec\u30f3\u30b7\u30f3\u30b0\u3084\u8ee2\u5199\u3001\u307e\u305f\u305d\u306e\u4ed6\u306e\u514d\u75ab\u53cd\u5fdc\u306a\u3069\u3001\u671f\u5f85\u901a\u308a\u306e\u7d4c\u8def\u53cd\u5fdc\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>MGS\u3068Nuvec\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u3053\u306e\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u306f\u3001\u7279\u5b9a\u306e\u7d30\u80de\u3092\u6a19\u7684\u306b\u51fa\u6765\u308b\u6f5c\u5728\u529b\u3092\u79d8\u3081\u3066\u304a\u308a\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u6cbb\u7642\u3092\u63d0\u4f9b\u3067\u304d\u308b\u3068\u3068\u3082\u306b\u3001\u30d7\u30ec\u30b7\u30b8\u30e7\u30f3\u30d8\u30eb\u30b9\u30b1\u30a2\u306e\u53ef\u80fd\u6027\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u305b\u307e\u3059\u3002<\/p>\n\n\n\n<p>SRI\u306e\u30d0\u30a4\u30aa\u30b5\u30a4\u30a8\u30f3\u30b9\u90e8\u9580\u306e\u30d7\u30ec\u30b8\u30c7\u30f3\u30c8\u3067\u3042\u308bKathlynn Brown\u306f\u3001\u300cN4 Pharma\u3068\u5354\u529b\u3057\u3066\u6838\u9178\u7642\u6cd5\u3092\u524d\u9032\u3055\u305b\u308b\u3068\u3068\u3082\u306b\u3001SRI\u306eFOX Three\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u3068\u3042\u308f\u305b\u3066\u540c\u793e\u306eNuvec\u30ca\u30ce\u7c92\u5b50\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u306e\u5fdc\u7528\u7bc4\u56f2\u3092\u62e1\u5927\u3067\u304d\u308b\u3053\u3068\u3092\u5b09\u3057\u304f\u601d\u3044\u307e\u3059\u300d\u3068\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u6cbb\u7642\u306e\u53ef\u80fd\u6027\u3092\u5e83\u3052\u308b<\/h2>\n\n\n\n<p>\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u304c\u9175\u7d20\u306b\u3088\u3063\u3066\u5206\u89e3\u3055\u308c\u308b\u3053\u3068\u3092\u9632\u304e\u3001\u8868\u9762\u7a4d\u304c\u5927\u304d\u3044\u305f\u3081\u8907\u6570\u306e\u30ab\u30fc\u30b4\uff08\u6cbb\u7642\u85ac\u306a\u3069\uff09\u3092\u9001\u9054\u3067\u304d\u308b\u3068\u3044\u3063\u305fNuvec\u306e\u4e3b\u306a\u7279\u5fb4\u3068\u3001MGS\u304c\u63d0\u4f9b\u3059\u308b\u30bf\u30fc\u30b2\u30c6\u30a3\u30f3\u30b0\uff08\u6cbb\u7642\u85ac\u304c\u5fc5\u8981\u306a\u7d30\u80de\u306e\u307f\u306b\u5c4a\u3051\u308b\uff09\u3092\u7d44\u307f\u5408\u308f\u305b\u308c\u3070\u3001\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u7642\u6cd5\u306e\u6d3b\u7528\u304c\u5927\u5e45\u306b\u4fc3\u9032\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3001\u3068Brown\u306f\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u300c\u3053\u306e\u6226\u7565\u7684\u30d1\u30fc\u30c8\u30ca\u30fc\u30b7\u30c3\u30d7\u306f\u6cbb\u7642\u306e\u53ef\u80fd\u6027\u3092\u62e1\u5927\u3059\u308b\u3068\u3068\u3082\u306b\u3001\u751f\u7269\u533b\u5b66\u306e\u5c55\u671b\u3092\u5909\u3048\u308b\u524d\u9014\u6709\u671b\u306a\u65c5\u306e\u59cb\u307e\u308a\u3092\u610f\u5473\u3057\u307e\u3059\u300d\u3068Brown\u306f\u8a9e\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>N4 Pharma\u306eNigel 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