SRI's translational neurosciences research laboratory provides investigative studies of complex cognitive processes utilizing customized, validated models that support research from rodent studies to human clinical trials. SRI manages a state-of-the-art laboratory that employs translational models to better understand complex biological and neurological disease mechanisms—and ultimately accelerate and minimize drug discovery risks and development to accelerate time to market for new treatments.

SRI’s in vivo efficacy testing services include a broad range of xenograft tumor models in mice, including SRI's customized patient derived cellular xenograft model - PDCellX™. PDCellX provides a more predictive model of human response in a variety of tissues and provides advantages such as custom biomarker and pharmacodynamic endpoint analysis and shorter tumor study timelines compared to standard PDX models.

SRI's preformulation and formulation services help optimize safety and efficacy in drug development. Our approach is customized according to each client’s program needs. Our drug formulation experience ranges from preparation of dose formulations for preclinical in vitro and in vivo safety studies, to design and manufacture of finished drug product dosage forms for clinical trials.