Medicinal Chemistry | SRI International

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Medicinal Chemistry

Medicinal Chemistry Services: Strategic Guidance and Consulting

SRI Biosciences provides medicinal chemistry strategic guidance and consulting services to help move your drug discovery projects forward, from Idea to IND and Beyond®.

We are a fully integrated organization with a rich history of discovering and developing novel “first-in-class” drugs from original concept to the FDA Investigational New Drug (IND) application and into human clinical trials. With more than 50 years of experience in small molecule drug discovery spanning multiple therapeutic areas and indications, we are well qualified to offer medicinal chemistry strategic guidance and consulting services for:

  • Reviewing projects and programs
  • Assessing drug-like properties of lead molecules
  • Creating compound candidate profiles
  • Developing optimization strategies
  • Designing new analogs
  • Synthesizing new analogs
  • Improving compound properties
  • Assessing progress
  • Troubleshooting specific optimization issues
  • Writing medicinal chemistry discussions for funding proposals
  • Expanding intellectual property

SRI Biosciences provides medicinal chemistry strategic guidance and consulting services to:

  • Pre-funding-stage start-ups
  • Small biotech companies
  • Companies looking for external review and ideation
  • Nonprofit and academic organizations

Work With the Experts 

SRI’s Medicinal Chemistry Services group is an integral part of SRI Biosciences. They have made significant contributions to the scientific community based on extensive applied knowledge and experience. (View a list of Medicinal Chemistry Publications authored by SRI Biosciences researchers). Their services can be applied at every stage of the drug discovery process (hit validation, hit-to-lead, and lead optimization) to help create and deliver effective candidates for further preclinical or clinical evaluations.

Specialized Services

As leaders in their fields, staff in Medicinal Chemistry Services offers strategic direction, intellectual input, and a complete, value-added approach to research.

For clients and partners needing direct access to a renowned team of medicinal chemists, we are unparalleled at supporting rapid, accurate, and efficient drug discovery and drug development.

Contact us to discuss how SRI Medicinal Chemistry Services can help you achieve your research goals.

Additional Expertise

Client investigators can also request specific medicinal chemistry contract services, such as custom drug synthesis and validated testing for physico-chemical, biological, and pharmacokinetic profiling, as well as custom assay development.

Projects

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Mechanism of Action of Praziquantel (PZQ)

SRI is elucidating the mechanism of action of the drug of choice for the treatment of all known forms of human schistosomiasis.

chemical diagram

Influenza RNA-dependent RNA polymerase (RdRp) Inhibitors

SRI is developing a new therapeutic agent for influenza virus infections.

graphic showing the hypothetical pharmacophore features for herboxidiene

Spliceosome Modulators as Antitumor Lead Compounds

SRI researchers are searching for new molecular targets that allow for discovery of more selective anticancer agents.

brain scan

Treatments for Narcolepsy

SRI sleep researchers are working to discover and develop new treatments for narcoleptic patients.