Projects | SRI International

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scientist with a computer model of a molecular structure
SRI is identifying candidates for advanced therapies in multiple disease areas by developing compounds from synthetically optimized, natural dietary products.
group of teens sitting together on the grass
SRI’s Sleep Research Laboratory in Menlo Park, California is currently recruiting for this study.
nicotine molecule with cigarettes
Researchers are seeking to identify novel genes contributing to nicotine metabolism and to smoking cessation.
nicotinic receptors affect brain activity
To support more effective cessation treatments, SRI researchers are exploring how nicotinic receptors affect brain activity in response to smoking.
diagram of nicotinic receptors
SRI is investigating whether the nicotine in tobacco smoke may be useful in meeting the urgent need to manage Parkinson’s disease.
man putting out a cigarette in an ashtray
This project could advance drug abuse prevention and intervention research by identifying Genetic x Environment (GxE) interactions, which may help explain the development of nicotine dependence. Results may guide development of tailored interventions.
middle-aged woman relaxing on bed
Sleep complaints are common during the transition to menopause, yet we have little understanding of what drives this increase in sleep disturbance and how best to treat it. SRI researchers are investigating sleep quality in women who have begun to go through menopause.
cigarette being snapped in half
SRI is analyzing the genetics of smoking and related characteristics, using data from a large-scale National Cancer Institute study on smoking cessation.
twin boys
SRI established the Twin Research Registry as part of its scientific research and efforts to discover more about human behavior. Fraternal and identical twins and multiples of all ages are invited to join the Registry for consideration for research studies.
Twins on bicycles
SRI studied twins to gain more clinical insight into physiologic response to powerful opioid painkillers. Study results should help to optimize pain relief and minimize adverse effects.
An SRI vaccine researcher in protective clothing and a mask
To help prepare for next-generation pandemics, SRI is partnering with Stanford University to examine vaccination responses.