EcoCyc: Encyclopedia of E. coli genes and metabolism


EcoCyc is an electronic reference source for biologists who work with E. coli and related microorganisms.

A member of the BioCyc Database Collection, EcoCyc is a bioinformatics database that describes the genome, metabolic network and regulatory network of Escherichia coli K-12 MG1655.

EcoCyc data is derived from:

  • Literature-based curation of the entire genome
  • Transcriptional regulatory network
  • Transporters
  • Metabolic pathways of E. coli

The project’s long-term goal is to facilitate a system-level understanding of E. coli by cataloging the cell’s molecular components and their functions.

The EcoCyc website supports comparative analyses of multiple E. coli strains and analysis of high-throughput data.

The project described was supported by Grant Number U24GM077678 from the National Institute of General Medical Sciences. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of General Medical Sciences or the National Institutes of Health.

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