Stein A., Juliano S., Karp P.D., Hand P. Computer-Assisted Three-Dimensional and Two-Dimensional Reconstructions of Autoradiographic Images of the Cerebral Cortex. Journal of Neuroscience Methods, 1984.
This report describes a computer system that generates reconstructions of film autoradiographs of the cerebral cortex. The reconstructions preserve 4 dimensions of the data including the (1) rostro-caudal and (2) medio-lateral cortical dimensions, (3) cortical thickness and (4) optical density value. This system is especially useful as it removes the subjectivity in analyzing the autoradiographs and provides a method for objectively reconstructing large amounts of data.