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Artificial intelligence publications November 1, 2012 Article

EcoCyc: Fusing Model Organism Databases with Systems Biology

SRI International November 1, 2012

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Keseler, I. M., Mackie, A., Peralta-Gil, M., Santos-Zavaleta, A., Gama-Castro, S., Bonavides-Martinez, C., . . . Karp, P. D. (2013). EcoCyc: fusing model organism databases with systems biology. Nucleic Acids Research, 41(D1), D605-D612. doi: 10.1093/nar/gks1027

Abstract

EcoCyc ( http://EcoCyc.org) is a model organism database built on the genome sequence of Escherichia coli K-12 MG1655. Expert manual curation of the functions of individual E. coli gene products in EcoCyc has been based on information found in the experimental literature for E. coli K-12-derived strains. Updates to EcoCyc content continue to improve the comprehensive picture of E. coli biology. The utility of EcoCyc is enhanced by new tools available on the EcoCyc web site, and the development of EcoCyc as a teaching tool is increasing the impact of the knowledge collected in EcoCyc.

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