Biomedical R&D services
SRI Biosciences provides research and services that span all stages of drug and diagnostics discovery and nonclinical development leading to human clinical trials and, ultimately, to the market.
SRI Biosciences conducts advanced, interdisciplinary research to tackle tough global health problems. We are a trusted government partner with decades of experience working with biopharma.
Ian M. Colrain
President, Biosciences Division
Featured innovators
Research and offerings
Basic research
Decades of fundamental research experience in disease mechanisms make SRI an ideal partner to solve your most difficult problems in drug development.
Drug and diagnostics discovery and development
SRI is creating new technology platforms for new generations of drug and diagnostics discovery and development.
Contract R&D services
SRI offers comprehensive contract services for discovery and development of drugs, biologics, devices and diagnostics.
Featured R&D services
SRI Biosciences partners with clients to seamlessly integrate basic research, drug discovery, and nonclinical and clinical development. See our full list of services below and fill out the contact form to learn more about how we can meet your specific needs.
Cancer efficacy evaluation
- SRI’s Cancer Research Center has a long history discovering and developing chemopreventives, chemotherapeutics and immunotherapeutics. Cancer efficacy testing includes in vitro screening panels and syngeneic and orthotopic cancer models.
Formulation and manufacturing (CMC)
- SRI’s preformulation and formulation services help optimize safety and efficacy in drug development. Offerings range from preparation of dose formulations for nonclinical in vitro and in vivo safety studies, to manufacture of finished drug product dosage forms for clinical trials.
Human sleep
- SRI’s Human Sleep Research Program conducts clinical and basic research; collaborates to develop novel device technologies for sleep research; provides proof-of-concept studies to support FDA IND files for central nervous system indications; and conducts FDA 510(k) trials for medical devices.
Clinical analysis laboratory
- SRI’s Clinical Analysis Laboratory provides expertise in clinical chemistry, hematology, coagulation, urinalysis, and blood gases. Fully compliant with FDA Good Laboratory Practice regulations, the lab uses state-of-the-art instrumentation and data management for human and veterinary clinical research samples.
Immunology assays
- SRI’s Immunology Services Facility provides services in immunology, virology, autoimmunity and inflammation including customized assay development and validation, as well as sample analysis for preclinical and clinical studies.
Virology models
- SRI’s virology services have the expertise to measure both immune and virology endpoints as well as efficacy in virology infection models of lymphocytic choriomeningitis virus (LCMV), HSV-1 and influenza PR8.
Custom synthesis and medicinal chemistry
- SRI’s Medicinal Chemistry and Strategic Guidance services support every stage of drug discovery (hit validation, hit-to-lead and lead optimization). We help create and deliver effective candidates for further evaluations including custom synthesis; validated testing for physico-chemical, biological and pharmacokinetic profiling; and custom assay development.
Proteomics and biomarker discovery and development
- SRI has extensive expertise in biomarker discovery and characterization and engages in independent, collaborative, or sponsored research for biomarker discovery and platform technology development.
Radiation efficacy and safety
- SRI’s radiation biology experts evaluate efficacy and safety to advance product development for radiation protection, decorporation and therapy—including small molecules and biologics for advancing new therapies or repurposing approved products. Resources include preclinical MRI for in vivo measurements of tissues.
R&D services
Our turnkey and customized services include models for research and drug discovery; identifying targets and mechanisms of action; efficacy; pharmacology and pharmacokinetics; and safety.
Discovery and basic research
- ADME
- Autoimmune/inflammation
- Biomarker discovery
- Cancer efficacy models
- Cell-based assays
- Cognition/learning/memory
- Custom synthesis
- Device evaluation
- Electrophysiology
- Imaging models
- Medicinal chemistry
- Neurological/neurodegenerative disorders
- Proteomics
- Radiation models
- Sleep, circadian rhythm
- Toxin models
- Viral models
Development services
- Analytical chemistry
- Bioanalytical chemistry
- Clinical laboratory services
- Clinical manufacturing
- Clinical trials
- Development and reproductive toxicology
- Formulation development
- Genetic toxicity
- Immunology assays
- Medical device development
- Molecular biology
- Pharmacokinetic/drug metabolism
- Radiation biology
- Toxicology and safety
Collaborative models
SRI Biosciences takes on the toughest biomedical challenges with transformative approaches and platforms. We partner closely with clients in areas including:
Co-development/licensing
Federal subcontract teaming
Grant teaming
Incubator space and services
Joint business partnerships
Regulatory support
Technology platforms
How can we help?
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We’ll match your inquiry to the person who can best help you. Expect a response within 48 hours.
