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Biosciences

We solve global health problems through cutting-edge interdisciplinary research.

SRI Biosciences works with academic, biopharmaceutical and biotechnology, foundation, and government clients and partners to bring new medicines and devices to market through basic research, pharmaceutical discovery, preclinical development and clinical translation. We have been a trusted partner to organizations worldwide for more than 50 years.

Today, combining the approaches of a nonprofit research institute, a biotech venture, and a contract research organization (CRO), SRI Biosciences integrates the R&D resources necessary to take drugs from Idea to IND® and beyond—from initial discoveries to first in human studies

Basic Biomedical Research

SRI Biosciences researchers solve important problems in prevention, diagnosis and treatment, targeting important unmet needs in healthcare and saving and improving lives worldwide. Our researchers strive to understand disease mechanisms, identify promising leads and translate preclinical candidates into clinical development. Core areas of therapeutic expertise include cancer, immunology and inflammation, infectious diseases and neuroscience. SRI also conducts bioscience R&D to produce new biomarkers, drug delivery technologies, medical devices, and systems biology tools.

Drug and Diagnostic Discovery

SRI Biosciences has discovered and developed marketed drugs such as Folotyn® (pralatrexate) and Targretin® (bexarotene) to treat various lymphomas; Ara-A® (Vidarabine) as an antiviral agent against Herpes simplex and Varicella zoster viruses; and Halfan® (halofantrine), to treat malaria. We have a full pipeline of new drugs and diagnostics in preclinical and clinical research.

Translational Development: Research and Development Services

In its capacity as a full-service CRO, SRI Biosciences has worked with clients and partners to conduct bioscience research and advance more than 100 drugs to human trials. SRI serves as a complete and reliable source for services ranging from idea to IND and beyond™, including synthesis, screening, efficacy, pharmacology, pharmacokinetics, safety, regulatory support, formulation, drug product manufacturing and early clinical trials. 

Contract Research Services

SRI Biosciences offers a broad array of contract R&D services, from in vivo assays to Phase 1 clinical trials. Learn more.

Locations

SRI Biosciences’ facilities at SRI headquarters in the San Francisco Bay Area consist of approximately 250,000 ft2 of basic R&D laboratory space, and include Good Laboratory Practices (GLP)- and Current Good Manufacturing Practices (cGMP)-compliant facilities. 

SRI Shenandoah Valley, a state-of-the-art 40,000-square-foot research facility in Harrisonburg, Virginia, focuses on health and biomedical research and drug discovery and development with the ultimate goal of bringing new therapies and diagnostics to market. The location also provides SRI Biosciences a convenient base for collaboration with private, government and academic institutions in Virginia and the greater Washington, D.C. area.

SRI’s Phase 1 Clinical Trial Facility occupies a purpose-built, approximately 9,400 square-foot expansion of the Michigan Life Science and Innovation Center in Plymouth, Michigan. The facility provides clients and partners with comprehensive early-stage human research capabilities for new medicines and medical devices.

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  • A world leader in the discovery and translation of innovative life sciences solutions, conducting R&D in cancer, immunology and infectious diseases.

  • Basic research, discovery and preclinical development services for cancer therapeutics, vaccines, and chemopreventive agents

  • Investigating the regulation of immunity and the mechanisms that contribute to disease, as well targeting autoimmune and inflammatory conditions

  • Investigating the regulation of immunity and the mechanisms that contribute to disease, as well identifying new approaches to defeating the world’s most significant infectious threats

  • Creating new opportunities and approaches for defeating the world’s most significant disease using the tools of chemistry

  • World-class basic scientific research, contract R&D, and state-of-the-art methodologies to advance programs in sleep, cognition, pain and addiction, obesity, Alzheimer's disease, Parkinson's disease, and aging, and to determine environmental, behavioral, and biological contributors to human health and illness.

  • Applying state-of-the art technologies and methodologies to determine environmental, behavioral, and biological contributors to human health and illness

  • Combining world-class basic scientific research with contract R&D to advance programs in sleep and circadian rhythms, cognition, pain and addiction, obesity, osteoporosis, and type 2 diabetes

  • Comprehensive services to move new drug candidates from the laboratory to clinical testing and into the marketplace.

  • Through our comprehensive drug metabolism, pharmacokinetics and toxicology services, SRI Biosciences helps you achieve your goals—from Idea to IND and beyond™.

  • Clinical trial execution and strategic guidance for biotech companies, university investigators and start-ups

  • High-quality GLP and non-GLP preclinical laboratory services in clinical chemistry, hematology, coagulation, urinalysis and specialized biomarkers

  • Transforming drug discovery and development

  • Preclinical and clinical drug formulation and manufacture of finished drug product for clinical trials

Find out more about SRI's proven, disciplined approach to innovation

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