Bergen, A. W., Javitz, H. S., Krasnow, R., Michel, M., Nishita, D., Conti, D. V., … & Swan, G. E. (2014). Organic cation transporter variation and response to smoking cessation therapies. nicotine & tobacco research, 16(12), 1638-1646.
We evaluated chr6q25.3 organic cation transporter gene (SLC22A1, SLC22A2, SLC22A3) variation and response to smoking cessation therapies. The corresponding proteins are low-affinity transporters of choline, acetylcholine and monoamines, and smoking cessation pharmacotherapies expressed in multiple tissues.