Author: SRI International
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High-Latitude Ionospheric Drivers and Their Effects on Wind Patterns in the Thermosphere
In this study, we investigate the ability of the Global Ionosphere-Thermosphere Model (GITM) to simulate the mesoscale wind structure over Alaska during a substorm.
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Characterization, HPLC Method Development and Impurity Identification for 3,4,3-Li(1,2-HOPO), a Potent Actinide Chelator for Radionuclide Decorporation
Derivatization of the target ligand in situ with Fe(III) chloride provided a single homogeneous iron-complex that can readily be detected and analyzed by HPLC.
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Measuring and Statistically Testing the Size of the Effect of a Chemical Compound on a Continuous in-Vitro Pharmacological Response through a New Statistical Model of Response Detection Limit
We used a linearized version of this equation to define a measure of pharmacological effect size, and use this measure to rank the investigated compounds in order of their overall capability to produce strong responses.
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BU08073 a Buprenorphine Analog with Partial Agonist Activity at mu Receptors in vitro but Long-Lasting Opioid Antagonist Activity in vivo in Mice
Structure activity studies were conducted to design buprenorphine analogues with high affinity at each of these receptors and to characterize them in in vitro and in vivo assays.
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Cytotoxicity of Human Endogenous Retrovirus K-Specific T Cells toward Autologous Ovarian Cancer Cells
Endogenous retroviral gene products in ovarian cancer may represent a potentially valuable new pool of tumor-associated antigens for targeting of therapeutic vaccines to ovarian cancer.
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Evidence for Effective Uses of Dynamic Visualisations in Science Curriculum Materials
We review research to clarify the impacts of dynamic visualisations and to identify instructional scaffolds that mediate their success.
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Evidence for Generation of Unstable Suprathermal Electron Population in the Auroral F Region
In this work we used a one-dimensional Zakharov simulation to constrain the range of physical mechanisms underlying these observational features.
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Singlet Molecular Oxygen Formation by O-Atom Recombination on Fused-Quartz Surfaces
Experimental results demonstrate O2(aΔ1g) (υ=0) formation by catalytic O-atom surface recombination in a room-temperature fused-quartz flow-tube reactor.
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The alpha7 Nicotinic Receptor Agonist ABT-107 Protects against Nigrostriatal Damage in Rats with Unilateral 6-Hydroxydopamine Lesions
The objective of this study was twofold: first, to test the protective potential of ABT-107, an agonist with high selectivity for α7 nAChRs; and second, to investigate its cellular mechanism of action.
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Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences
To assess the relative contribution of heritable versus non-heritable factors, we have performed a systems-level analysis of 210 healthy twins between 8 and 82 years of age.
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Feature Fusion by Similarity Regression for Logo Retrieval
We propose a simple yet effective multi-feature fusion approach based on regression models for logo retrieval.
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ENHANCE: Studying the Quality of Child Outcomes Data
ENHANCE consisted of four studies that examined the quality of the data that was collected through the Child Outcomes Summary (COS) process.