Author: SRI International
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An Enhanced β Turn in Water
A series of tetrapeptides based on the sequence Ac-Ala-Pro-Ala-Ala-NH2 containing all possible combinations of l- and d-amino acids was synthesized.
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Organizing Research and Development at the Intersection of Learning, Implementation, and Design
This article describes elements of an approach to research and development called design-based implementation research.
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Sharing Models and Research to Build Leadership in Program Improvement
SRI designed an online community architecture that permits faculty from small departments in different community colleges to share ideas about how to integrate PBL into their classrooms. This presentation presents an overview of the architecture.
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Honeynet Games: a Game Theoretic Approach to Defending Network Monitors
We formalize the problem of defending honeynets from systematic mapping (a serious threat to their viability) as a simple two-person game.
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Quantification of in Vivo Metabolic Kinetics of Hyperpolarized Pyruvate in Rat Kidneys Using Dynamic 13C MRSI
We developed an efficient quantification framework employing a spiral-based dynamic spectroscopic imaging approach.
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Anatomic Closure of the Premature Patent Ductus Arteriosus: the Role of CD14+/CD163+ Mononuclear Cells and VEGF in Neointimal Mound Formation
We hypothesized that VEGF plays a crucial role in attracting CD14/CD163 mononuclear cells to the ductus lumen and that CD14/CD163 cell adhesion to the ductus lumen is important for neointimal growth.
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A Gene Expression Signature from Peripheral Whole Blood for Stage I Lung Adenocarcinoma
We measured gene expression from lung tissue and peripheral whole blood from adenocarcinoma cases and controls to identify dysregulated lung cancer genes that could be tested in blood to improve identification of at-risk patients in the future.
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Enteric Microbiome Metabolites Correlate with Response to Simvastatin Treatment
We used a targeted GC-MS metabolomics platform to measure a panel of metabolites that may predict variation in statin LDL-C lowering efficacy.
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Comparison of Binding and Functional Activity Profiles for a Set of Nicotinic Acetylcholine Receptor Ligands Across Multiple Alpha 6*Expression Systems
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Realizing the value of social media requires innovative computing research
How social media are expanding traditional research and development topics for computer and information scientists.
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Is the organizational computer a digital nervous system?
This talk is about the questions we are asking ourselves as we design and field these systems, where their power comes from, how they are being created by multidisciplinary technology teams and ethnographers, how we are managing, prioritizing and accelerating the necessary innovations, and what we are learning from them.
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A graph lattice approach to maintaining dense collections of subgraphs as image features
This paper shows how large families of complex features can be built out of simpler ones through construction of a graph lattice – a hierarchy of related subgraphs linked in a lattice.