FOX Three Molecular Guidance System

Cancer cell being targeted

SRI’s FOX Three platform enables cell-selective, intracellular delivery of macromolecular cargoes for applications such as cancer diagnosis and treatment. Leveraging a peptide-based Molecular Guidance System™, the platform delivers large-molecule payloads to targeted cells while avoiding healthy tissues. These payloads can include protein toxins, antibodies, nucleic acids (DNA/RNA), liposomes, and nanoparticles.

FOX Three’s capabilities have advanced precision health programs for ARPA-H and multiple bioscience startups.


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