SRI International
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Twins Hold Special Role in Medical Science
Twins hold a special place in medical science by uniquely providing insight into how behavior and genetics affect disease, aging, and response to medical treatments. Through twin studies, scientists understand the interplay between genetics and the environment in ways that the study of unrelated people–or even other types of siblings–is unable to do. Because identical…
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Measuring learning progressions using bayesian modeling in complex assessments
This research examines issues regarding model estimation and robustness in the use of Bayesian Inference Networks (BINs) for measuring Learning Progressions (LPs).
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Fast and private computation of cardinality of set intersection and union
This paper explores a few PSI-CA variations and constructs several protocols that are more efficient than the state-of-the-art.
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“Black Marble”: Stunning Views of the Earth at Night
This composite image of the world, called the “Black Marble,” was taken with the day-night band of NASA’s Visible Infrared Imaging Radiometer Suite (VIIRS). The day-night band sensor in the instrument was designed and developed by SRI using the latest extended dynamic range charge-coupled device (CCD) technology that can capture the finest details, even in…
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1968 “Mother of All Demos” Forecasted Much of the Technology We Use Every Day
We all have our share of anniversaries to remember, but here’s one that has impacted all of our lives: on December 9, 1968, Douglas Engelbart and his SRI team delivered what has come to be known as the “Mother of All Demos.” Hard to believe, but in one presentation, Dr. Engelbart and his Augmentation Research…
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Targeting Glioblastoma Stem Cells: Cell Surface Markers
In this review, we primarily summarize recent advances in identification of GSC markers, with a particular focus on cell surface markers.
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Latent Profiles of Problem Behavior within Learning, Peer, and Teacher Contexts: Identifying Subgroups of Children at Academic Risk across the Preschool Year
Employing a developmental and ecological model, the study identified initial levels and rates of change in academic skills for subgroups of preschool children exhibiting problem behavior within routine classroom situations.
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Gender-Stratified Gene and Gene-Treatment Interactions in Smoking Cessation
We conducted gender-stratified analyses on a systems-based candidate gene study of regions involved in nicotinic response and the brain—reward pathway in two randomized clinical trials of smoking cessation treatments (placebo, bupropion, transdermal and nasal spray nicotine replacement therapy).
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Replaying the Fracture Process of a Failed Space Shuttle Orbiter Thruster
The work shows how a failure event can be replayed through fracture surface topography analysis, FRASTA, and how information on load conditions, relative crack growth rates, and fracture mechanics parameters may be extracted from fracture surfaces.
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The DRD4 Exon III VNTR, Bupropion, and Associations with Prospective Abstinence
We used univariate, multivariate, and longitudinal logistic regression to evaluate effects on point prevalence and continuous abstinence at end of treatment in European ancestry participants in a trial randomizing participants to active or placebo bupropion.
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Catalytic Detoxification of Nerve Agent and Pesticide Organophosphates by Butyrylcholinesterase Assisted with Non-Pyridinium Oximes
In the present paper we show a comprehensive study on hydrolytic detoxification of nerve agent and pesticide OPs catalysed by purified hBChE in combination with novel non-pyridinium oxime reactivators.
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Implementation of an Augmented Reality System for Training Dismounted Warfighters
We describe the technical methods and experimental results on building an Augmented Reality Training system for training dismounts doing maneuver operations.