SRI International
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A Single Algorithm Combining Exposure and Focus Fusion
This paper proposes an overhauled method of exposure fusion that solves the exposure and focus problems simultaneously, achieving a well-exposed, all-in-focus result.
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Neglected Diseases: In Need of Bare Necessities and Breakthroughs
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Immunoregulatory and Effector Activities in Human Cutaneous and Mucosal Leishmaniasis: Understanding Mechanisms of Pathology
By studying the immune response from CL and ML patients in both the peripheral blood and in situ, we have learned much concerning the dynamics of the host–pathogen interaction that leads to the development of CL and ML.
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The Biason the Joule Heating Estimate: Small-Scale Variability Versus Resolved-Scale Model Uncertainty and the Correlation of Electric Field and Conductance
In this work we separately analyze the small-scale variability and the resolved-scale model uncertainty using the Sondrestrom radar database, and we find that each gives a significant contribution to the bias on Joule heating.
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A Survey of Metabolic Databases Emphasizing the Metacyc Family
The main families are the MetaCyc, KEGG, Reactome, Model SEED, and BiGG families. We survey these database families, as well as important individual metabolic databases, including multiple human metabolic databases.
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Analytical Methods for the Bioavailability Evaluation of Hydroxypryridinonate Actinide Decorporation Agents in Pre-clinical Pharmacokinetic Studies
The described bioanalytical detection methods were successfully applied to the selection of solid-state forms of 5-LIO and 3,4,3-LI for future preclinical development activities, and will be adapted for use with plasma from other species.
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Climate-Monitoring Cubesat Mission (Cm2): a Project for Global Mesopause Temperature Sensing
This paper outlines an instrument to advance the state of the art in atmospheric climate projection by providing critical global measurements of middle-atmosphere temperatures and waves with a CubeSatscale imaging spectrograph.
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The Electron Density Dependence of Polar Mesospheric Summer Echoes
We present several observations made using the Poker Flat Incoherent Scatter Radar which are difficult to explain based on those expressions, including observations at night with no detectable incoherent scatter below 90 km and during aurora where the reflectivity shows no response to abrupt changes in ionization.
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CD4(+) T Cells Defined By Their V Beta T Cell Receptor Expression Are Associated with Immunoregulatory Profiles and Lesion Size in Human Leishmaniasis
In order to measure the host T cell response to Leishmania infection, we have measured the expansion, activation state and functional potential of specific T cells as identified by their T cell receptor Vβ region expression.
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Multi-Modality Imaging Assessment of Alcoholism’s Damaging Effect on Brain Systems and Circuitry
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Partnership Research for Advanced Technological Education (ATE)
SRI researchers are conducting case studies of how such partnerships are established and sustained.
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Clinical Aspects of Chagas Disease and Implications for Novel Therapies
The interaction between the protozoan parasite Trypanosoma cruzi and the human host dates back 9,000 years, as demonstrated by molecular analysis of material obtained from Andean mummies indicating the presence of the parasite’s kinetoplast DNA in populations from Chile and Peru.