Peter Karp
Technical Director, Artificial Intelligence Center
Peter Karp, Ph.D., Technical Director of the Bioinformatics Research Group at SRI International, works in the interdisciplinary field of bioinformatics, which develops computer-science methods for managing and analyzing the burgeoning quantities of biological data and knowledge.
Karp has been a pioneer in metabolic-pathway bioinformatics. His group has developed a metabolic-pathway database called EcoCyc that charts the complete biochemical factory within an Escherichia coli cell. His group has also developed algorithms for visualization of metabolic networks, for predicting anti-bacterial drug targets within metabolic networks, and for predicting the metabolic pathways of an organism whose genome has been sequenced. The latter algorithm has been applied to thousands of organisms to produce the BioCyc database collection.
Karp has authored more than 190 publications in computer science and bioinformatics. He is an SRI Fellow, a Fellow of the International Society for Computational Biology, and a Fellow of the American Association for the Advancement of Science.
Recent publications
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The Comparative Genome Dashboard
The Comparative Genome Dashboard is a web-based software tool for interactive exploration of the similarities and differences in gene functions between organisms.
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The Genome Explorer Genome Browser
In this paper we report on a major update to our browser, Genome Explorer, that provides nearly instantaneous scaling and traversing of a genome, enabling users to quickly and easily…
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An Evaluation of ChatGPT and Bard (Gemini) in the Context of Biological Knowledge Retrieval
We evaluate the effectiveness of chatbots in retrieving biological knowledge for curation and research purposes.
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CyanoCyc Cyanobacterial Web Portal
CyanoCyc is a web portal that integrates an exceptionally rich database collection of information about cyanobacterial genomes with an extensive suite of bioinformatics tools.
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The Omics Dashboard for Interactive Exploration of Metabolomics and Multi-Omics Data
The Omics Dashboard is a software tool for interactive exploration and analysis of metabolomics, transcriptomics, proteomics, and multi-omics datasets.
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The EcoCyc Database (2023)
The long-term goal of the project is to describe the complete molecular catalog of the E. coli cell, as well as the functions of each of its molecular parts, to…