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Home » Archives for Adolf Pfefferbaum » Page 2
Adolf Pfefferbaum

Adolf Pfefferbaum

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Publications

Biomedical sciences publications January 8, 2022

Aging Accelerates Postural Instability in HIV Infection: Contributing Sensory Biomarkers

Adolf Pfefferbaum

Whether aging with HIV accelerates age-related liability for postural instability and what sensory factors contribute to imbalance were examined in 227 PWH and 137 people living without HIV (PWoH), age 25 to 75 years.

Biomedical sciences publications November 20, 2021

Neurobiology of Alcohol Dependence: Focus on Motivational Mechanisms 

Adolf Pfefferbaum

Recent research focusing on brain arousal, reward, and stress systems is accelerating our understanding of the components of alcohol dependence and contributing to the development of new treatment strategies.  

Biomedical sciences publications August 1, 2015

Cognitive Demands During Quiet Standing Elicit Truncal Tremor in Two Frequency Bands: Differential Relations to Tissue Integrity of Corticospinal Tracts and Cortical Targets

Natalie Zahr, Adolf Pfefferbaum

Given the complexity of sensorimotor integration invoked to maintain upright posture, the integrity of supratentorial brain structures may also contribute to quiet standing and consequently be vulnerable to interference from cognitive challenges.

Biomedical sciences publications April 1, 2015 Article

Dynamic Responses of Selective Brain White Matter Fiber Tracts to Binge Alcohol and Recovery in the Rat

Adolf Pfefferbaum, Natalie Zahr

To determine the dynamics of white matter vulnerability to excessive alcohol consumption, diffusion tensor imaging (DTI) was used in an animal model of alcohol exposure.

Biomedical sciences publications January 1, 2015

Quantitative Susceptibility Mapping by Inversion of a Perturbation Field Model: Correlation with Brain Iron in Normal Aging

Adolf Pfefferbaum

We present a method for quantifying susceptibility by inversion of a perturbation model, or “QSIP.” The perturbation model relates phase to susceptibility using a kernel calculated in the spatial domain, in contrast to previous Fourier-based techniques.

Biomedical sciences publications December 1, 2014

Compromised Frontocerebellar Circuitry Contributes to Nonplanning Impulsivity in Recovering Alcoholics

Tilman Schulte, Adolf Pfefferbaum

We tested the hypothesis that alcoholic patients would demonstrate compromised dorsal anterior cingulate cortex (dACC) -cerebellar functional connectivity when adjusting their strategies to accommodate uncertain conditions and would recruit compensatory brain regions to overcome ineffective response patterns.

Biomedical sciences publications November 1, 2014

Interhemispheric Functional Connectivity Change Is Linked to Callosal Fiber Integrity Change over a 1-Year Follow-up in Chronic Alcoholics

Adolf Pfefferbaum, Tilman Schulte

We tested whether microstructural fiber changes relate to resting-state functional connectivity changes in alcoholics who have maintained sobriety during a one-year interval, and whether these changes are beyond those potentially exhibited by controls.

Biomedical sciences publications November 1, 2014

Imaging Neuroinflammation? A Perspective from MR Spectroscopy

SRI International, Natalie Zahr, Adolf Pfefferbaum

The present MRS study was conducted in four groups: alcohol dependent, HIV-infected, alcohol dependent + HIV infected and healthy control individuals to determine whether metabolites would change in a pattern reflecting neuroinflammation.

Biomedical sciences publications June 1, 2014 Conference Paper

In Vivo Diffusion Tensor Imaging Evidence for Reversible White Matter Microstructural Integrity Disruption: Effects of Abstinence in Rat and Man

SRI International, Natalie Zahr, Adolf Pfefferbaum

SRI Authors: Natalie Zahr, Adolf Pfefferbaum

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