Author: SRI International
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The Acute and Chronic Effects of Alcohol Consumption on Sleep Architecture in College Aged Students
This study examined the effect of alcohol on sleep architecture in women and men aged 18 to 21 years and whether previously reported sleep architecture effects may have been as an artificial result of changes to sleep cycle length.
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Effect of Bitopertin, a Glycine Reuptake Inhibitor, on Negative Symptoms of Schizophrenia: A Randomized, Double-Blind, Proof-of-Concept Study
Our objective is to determine the efficacy and safety of bitopertin (RG1678), a glycine reuptake inhibitor, in patients with schizophrenia and predominant negative symptoms who were stable while taking an antipsychotic treatment.
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Sample Collection in Clinical Proteomics – Proteolytic Activity Profile of Serum and Plasma
We utilized the platform to ascertain the impact of three commonly used anticoagulants (EDTA, heparin, and citrate) on the proteolytic activity profile of plasma and serum collected from a healthy Caucasian male.
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PIDGIN: Privacy-Preserving Interest and Content Sharing in Opportunistic Networks
This paper addresses the research challenges inherent to the exchange of content and interests without compromising the privacy of subscribers, and allowing unauthorised access to untrusted brokers. Specifically, this paper presents an interest and content sharing solution that addresses these security challenges and preserves privacy in opportunistic networks.
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Permeability Enhancing Lipid-Based Co-Solvent and SEDDS Formulations of SQ641, an Antimycobacterial Agent
The objective of this study was to develop an oral preclinical liquid formulation of SQ641 and to determine the permeability across rat intestinal tissue by Ussing chamber.
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Evidence for the Role of EPHX Gene Variants in Anorexia Nervosa
To identify genetic variants associated with AN, we pursued a series of sequencing and genotyping studies focusing on the coding regions and upstream sequence of 152 candidate genes in a total of 1205 AN cases and 1948 controls.
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Implementation of an Intelligent Tutoring System for Online Homework Support at Large Scale
In this paper, we describe an ongoing randomized controlled trial (RCT) to evaluate the efficacy of a web-based tutoring system—the ASSISTments—as support for homework.
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Implementation of an Intelligent Tutoring System for Online Homework Support in an Efficacy Trial
In this paper, we describe an ongoing randomized controlled trial (RCT) to evaluate the efficacy of a web-based tutoring system—the ASSISTments—as support for homework.
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A Design Inquiry: Bridging Assessment and Curriculum Frameworks to Engage Students in Science Practices
This reflective inquiry delves into the collaborative design process of a technology based middle school genetics unit. With a lens on science practices, we describe how bridging assessment and curriculum design frameworks can inform decisions in an iterative co-design process.
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Curation Accuracy of Model Organism Databases
We assessed the accuracy of EcoCyc and CGD by manually selecting curated assertions within randomly chosen EcoCyc and CGD gene pages and by then validating that the data found in the referenced publications supported those assertions.
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Implementation Science in School Mental Health: Key Constructs in a Developing Research Agenda
In this paper, we propose an implementation science research agenda as it applies to school mental health (SMH).
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Radiation induced defects in poly(3-alkylthiophene)
We therefore will discuss density functional calculations of the energy barriers that must be surmounted to form hydrogen related defects in polymers such as poly(3-alkylthiophene).