Author: SRI International
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Distinct Loci in the CHRNA5/CHRNA3/CHRNB4 Gene Cluster Are Associated with Onset of Regular Smoking
This meta-analysis examines early smoking phenotypes and SNPs in the gene cluster to determine: (1) whether the most robust association signal in this region (rs16969968) for other smoking behaviors is also associated with early behaviors, and/or (2) if additional statistically independent signals are important in early smoking.
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Textile Damage in Astronaut Gloves
This article describes the damage observations and results of the laboratory tests, deduces how the damage occurred, and presents guidelines for designing gloves that are more damage resistant.
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Comparison of SuperDARN Irregularity Drift Measurements and F-Region Ion Velocities from the Resolute Bay ISR
This work is motivated by testing the same assumption on a more optimal experimental setting: using the north face of the Resolute Bay incoherent scatter radar (RISR-N) thereby reducing echo mixing due to spatio-temporal structuring.
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Ion-Neutral Coupling in Earth’s Thermosphere, Estimated from Concurrent Radar and Optical Observations above Alaska
We report on data collected during the campaign, and use these data to investigate two key aspects of ion–neutral coupling, namely Joule heating and the ion–neutral collision frequency.
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Long-Term Nicotine Treatment Down-Regulates Alpha 6 Beta 2* Nicotinic Receptor Expression and Function in Nucleus Accumbens
We therefore treated rats for 2–3 months with nicotine and examined alterations in nAChR subtype expression and electrically evoked dopamine release in rat nucleus accumbens shell, a region key in addiction.
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Intelligent Learning Technologies: Applications of Artificial Intelligence to Contemporary and Emerging Educational Challenges
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Intelligent Learning Technologies Part 2: Applications of Artificial Intelligence to Contemporary and Emerging Educational Challenges
The issue concludes with an article summarizing the contemporary and emerging challenges at the intersection of AI and education.
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A comparison study of user behavior on Facebook and Gmail
In this paper, we collected objective, privacy-preserved behavior data from participants that were both active Facebook and Gmail users.
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Online reconfigurable machines
We propose an approach to achieving online reconfigurability based on a high level of system modularity supported by integrated, model-based planning and control software.
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Wellness Tourism is a Growth Opportunity Worldwide
Ask individuals how healthy they feel when traveling, and you’re more likely to hear a litany of complaints than a list of benefits. Even when we take a vacation to unwind, jet lag, missing sleep, unhealthy meals, and disrupted exercise routines are side effects of the way we travel, whether for business or for pleasure.…
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Veterans’ Experience is Valuable to SRI International and the Clients We Serve
As a veteran of the Vietnam War and a graduate of West Point, Veterans Day touches me personally and professionally. It’s vitally important that as a nation we have a day that recognizes those who are serving—and those who have served—in the United States Armed Forces. It brings both a sense of history and purpose…
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Varenicline Markedly Decreases Antipsychotic-Induced Tardive Dyskinesia in a Rodent Model
Tardive dyskinesia is a potentially irreversible drug-induced movement disorder that arises as a side effect of antipsychotic therapy. Antipsychotics form the mainstay of treatment for schizophrenia and bipolar disorder and, in addition, are increasingly being prescribed for major depressive disorder, autism, attention deficit hyperactivity disorder, obsessive compulsive disorder and post-traumatic stress disorder. There is therefore…