Biomedical sciences publications
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Absence of Association Between Specific Common Variants of the Obesity-Related Fto Gene and Psychological and Behavioral Eating Disorder Phenotypes
To determine whether FTO may influence weight regulation through psychological and behavioral factors, seven single-nucleotide polymorphisms of the FTO gene were genotyped in individuals with anorexia nervosa (AN) and 677…
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The Combination of Cobinamide and Sulfanegen Is Highly Effective in Mouse Models of Cyanide Poisoning
We are developing two new cyanide antidotes—cobinamide, a vitamin B12 analog, and sulfanegen, a 3-mercaptopyruvate prodrug. Both drugs can be given by intramuscular administration, and therefore could be used to…
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Effects of Acute Alcohol on Sleep Evoked Potentials in Heavy Drinking and Light Drinking Male College Students
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Personality Disorders in Women with Severe Premenstrual Syndrome
The comorbidity of a personality disorder and severe PMS places an additive burden on general life functioning and may have implications for psychiatric treatment or medication given to those with…
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Synthesis of 3H-Labeled Tetrabenazine (TBZ)
Our method provides tritium-labeled TBZ with high specific activity and radiochemical purity, which allow the further investigation of a TBZ in the neurological field.
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Multiple Gap-Filling of Flux-Balance Models
Keywords: Artificial Intelligence, Artificial Intelligence Center, AIC
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Substrate Specifity Profiling of the Aspergillus Fumigatus Proteolytic Secretome Reveals Consensus Motifs with Predominance of Ile/Leu and Phe/Tyr
This report provides proof-of-principle for the use of protease substrate specificity profiling to define the proteolytic secretome of Aspergillus fumigatus.
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Iron-Ion Radiation Accelerates Atherosclerosis in Apolipoprotein E-Deficient Mice
Recently, concern over whether exposure to cosmic radiation might pose a similar risk for astronauts has increased. To address this question, we examined the effect of 2 to 5 Gy iron…
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Epstein-Barr Virus Micrornas and Lung Cancer
We conducted the first analysis of viral microRNAs (miRNAs) in lung cancer, with a focus on Epstein–Barr virus (EBV).
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Effect of Fenoterol Stereochemistry on the β2 Adrenergic Receptor System: Ligand-Directed Chiral Recognition
The β2 adrenergic receptor (β2-AR) is a model system for studying the ligand recognition process in G protein-coupled receptors. Fenoterol (FEN) is a β2-AR selective agonist that has two centers of…
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Nicotinic Receptor Agonists Decrease L-Dopa-Induced Dyskinesias Most Effectively in Partially Lesioned Parkinsonian Rats
To further understand how nicotine mediates its antidyskinetic action, we investigated the effect of nicotinic receptor (nAChR) agonists in unilateral 6-OHDA-lesioned rats with varying striatal damage.
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Disruption of Emotion and Conflict Processing in HIV Infection with and Without Alcoholism Comorbidity
We investigated whether patients with alcoholism, HIV-1 infection, or both diseases have greater difficulty than healthy controls in resolving conflict from emotional words with different valences.