We present the first structural and mechanistic model for the evolutionary emergence of TPS function in insects. Through identifying key mechanistic differences between IDS and TPS enzymes, we hypothesize that the loss of isopentenyl diphosphate (IPP) binding motifs strongly correlates with the gain of the TPS function.
Publications
Effects of the COVID-19 pandemic on screen time and sleep in early adolescents
This study examined changes in sleep habits and recreational screen time (social media, video gaming), and their relationship, before and across the first year of the pandemic in adolescents in the Adolescent Brain Cognitive Development (ABCD) Study.
Night-Time GPS-Denied Navigation and Situational Understanding Using Vision-Enhanced Low-Light Imager
In this presentation, we describe and demonstrate a novel vision-enhanced low-light imager system to provide GPS-denied navigation and ML-based visual scene understanding capabilities for both day and night operations.
Vision based Navigation using Cross-View Geo-registration for Outdoor Augmented Reality and Navigation Applications
In this work, we present a new vision-based cross-view geo-localization solution matching camera images to a 2D satellite/ overhead reference image database. We present solutions for both coarse search for cold start and fine alignment for continuous refinement.
Cross-View Visual Geo-Localization for Outdoor Augmented Reality
We address the problem of geo-pose estimation by cross-view matching of query ground images to a geo-referenced aerial satellite image database. Recently, neural network-based methods have shown state-of-the-art performance in cross-view matching.
Genetically engineered pair of cells for serological testing and its application for SARS-CoV-2
We have developed a serology test platform for identifying individuals with prior exposure to specific viral infections and provide data to help reduce public health risks.
Good Sleep is a Mood Buffer for Young Women During Menses
We sought to elucidate the interaction between sleep and mood considering menstrual cycle phase in 72 healthy young women with natural, regular menstrual cycles and without menstrual-associated disorders.
Activation of the nociceptin/orphanin-FQ receptor promotes NREM sleep and EEG slow wave activity
In the present study, we systematically evaluated the efficacy of two NOPR agonists, Ro64-6198 and SR16835, on sleep/wake in rats, mice, and Cynomolgus macaques.
Morning perception of sleep, stress, and mood, and its relationship with overnight physiological sleep: findings from the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) study
This cross-sectional study investigated objective–subjective sleep discrepancies and the physiological basis for morning perceptions of sleep, mood, and readiness, in adolescents.