Biomedical sciences publications
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Functional IL-10 Gene Polymorphism is Associated with Chagas Disease Cardiomyopathy
This study was designed to determine whether the functional IL-10 gene polymorphism −1082G/A is associated with the development of cardiomyopathy in individuals infected with Trypanosoma cruzi.
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A Consensus Definition of Cataplexy in Mouse Models of Narcolepsy
To establish a common language, the International Working Group on Rodent Models of Narcolepsy reviewed the literature on cataplexy in people with narcolepsy and in dog and mouse models of…
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Choline Acetyltransferase Expression During Spontaneous Sleep-Wake Bouts Over 24H
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Enhanced Alpha-Synuclein Expression in Human Neurodegenerative Diseases: Pathogenetic and Therapeutic Implications
Here we discuss the possibility that other mechanisms of alpha-synuclein elevation contribute to the pathogenesis of idiopathic, sporadic Parkinson's disease and other human synucleinopathies.
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Expression of Plasticity-Related Genes During Eszopiclone-Induced Sleep
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Nociceptin/Orphanin FQ Antagonists Ameliorate the Disease Pathogenesis During Inflammatory Bowel Disease
We evaluated the therapeutic potential of N/OFQ antagonists in C57Bl/6 mice in an IBD model after disease induction by treatment for 5 days with DSS, and subsequent observation of the…
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Therapeutic Efficacy of a Melatonin Agonist, Ramelteon, and a Benzodiazepine, Triazolam, in a Mouse Genetic Model of Advanced Sleep Phase Syndrome
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Pharmacokinetics and Immunogenicity Assays for a Human Monoclonal Antibody Mixture Specific for Botulinum Neurotoxin A
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Identification of “Sleep Genes” from Natural and Pharmacologically Induced Sleep Studies
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Processing of Emotional and Alcohol Stimuli in Chronic Alcoholism
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Subject-Matched Templates for Spatial Normalization
Here, we introduce the concept of subject-matched templates. Rather than using a single template for the entire population, a different template is used for every subject, with the template matched…
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The Impact of Alcoholism in Men and Women on Polysomnography and Sleep EEG