SRI International
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Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor
The influenza endonuclease is an essential subdomain of the viral RNA polymerase. It processes host pre-mRNAs to serve as primers for viral mRNA and is an attractive target for antiinfluenza drug discovery.
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Empowering Adults to Thrive at Work: Personal Success Skills for 21st Century Jobs. A Report on Promising Research and Practice
From interviews with experts and a review of research literature, the report provides resources and recommendations to advance practice, research, and policy.
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Validity of the data from the child outcomes summary process: Findings from the ENHANCE Project
This brief describes findings from the ENHANCE study that sought to answer the question of whether the Child Outcomes Summary (COS) process produces valid ratings for measuring the child outcomes achieved through early intervention (EI) and early childhood special education (ECSE) programs.
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High performance diagnostic platforms for uncovering micro-/nano-environmental heterogeneity within aggressive cancer cells
We are exploring spatiotemporal characteristics and physicochemical identities of solid breast cancer cells and their micro/nanoenvironments in relation to tumor aggression.
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Radiative Cooling Holds Promise for Thermoelectric Power Plants
The U.S. Department of Energy’s ARPA-E ARID program is exploring novel ways to use air-cooled heat exchangers and supplemental cooling systems to carry away waste heat in thermoelectric power generation.
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Toward Interactive Relational Learning
This paper introduces the Interactive Relational Machine Learning (iRML) paradigm in which users interactively design relational models by specifying the various components, constraints, and relational data representation, as well as perform evaluation, analyze errors, and make adjustments and refinements in a closed-loop.
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Combining Capabilities to Address the Zika Emergency
Although discovered in the late 1940s, the Zika virus was not well studied until recently. Zika is not a life-threatening disease for adults, and didn’t attract the attention of most researchers who study mosquito-borne diseases until this past year, when the number of cases increased dramatically in South and Central America. In fact, it’s likely…
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Heat-Switch-Based Electrocaloric Cooling (invited)
This talk will cover work modeling, designing, building, and testing a heat-switch-based electrocaloric heat pump.
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Quantitative Electroencephalographic Analysis Provides an Early-Stage Indicator of Disease Onset and Progression in the zQ175 Knock-In Mouse Model of Huntington’s Disease
We used a full-length knock-in HD model to determine early changes in the electroencephalogram (EEG) and sleep that may predict the onset and progression of the disease.
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Classroom trials: A study of instruction with writing software
This was a descriptive study on how secondary teachers implementing the Common Core State Standards for literacy used writing software to facilitate their instruction.
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21st Century Science Assessment: The Future Is Now
SRI Education recruited three education policy experts to contributed concept papers that explore the research and policy implications of the STEM indicators system.
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21st Century Science Assessment: The Future Is Now – Executive Summary
In this paper, Jim Pellegrino of the University of Illinois at Chicago presents a vision for a balanced and coordinated system of STEM assessments that work together, and with curriculum and instruction, to promote effective science teaching and learning.