SRI International
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Automated, Adaptive Guidance for K-12 Education
This paper distinguishes features of automated adaptive guidance used in K-12 instructional settings and recommends directions for design.
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Brain Development in Heavy-Drinking Adolescents
The authors measured within-subject changes in regional brain morphometry over longer intervals and in larger samples of adolescents than previously reported and assessed differences between adolescents who remained nondrinkers and those who drank heavily during adolescence as well as differences between the sexes.
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Women with Dysmenorrhoea Are Hypersensitive to Experimentally Induced Forearm Ischaemia During Painful Menstruation and During the Pain-Free Follicular Phase
We investigated whether women with dysmenorrhoea, compared with controls, have increased sensitivity to experimentally induced deep-tissue muscle ischaemia in a body area distant from that of referred menstrual pain.
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Early Math with Gracie & Friends (Tm) Demo: App-Infused Curriculum and Teacher Support for Preschool
Our team developed and published eight iPad apps, 38 hands-on activities, a digital Teacher’s Guide, and professional development modules to help preschool children learn foundational math concepts.
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Insomnia in Women Approaching Menopause: Beyond Perception
We aimed to quantify sleep disturbance and the underlying contribution of objective hot flashes in 72 women who had, compared to those who had not, developed clinical insomnia in association with the menopausal transition.
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Cardiac Autonomic Function During Sleep: Effects of Alcohol Dependence and Evidence of Partial Recovery with Abstinence
Chronic alcoholism is associated with the development of cardiac and peripheral autonomic nervous system (ANS) pathology.
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Design and Verification for Transportation System Security
In this work, we propose an integrated framework that combines hybrid modeling, formal verification, and automated synthesis techniques for analyzing the security and safety of transportation systems and carrying out design space exploration of both in-vehicle electronic control systems and vehicle-to-vehicle communications.
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Clock Genes X Stress X Reward Interactions in Alcohol and Substance Use Disorders
The aim of the present review is to summarize findings linking clock genes, stress, and alcohol and substance abuse, and to propose potential underlying neurobiological mechanisms.
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Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery
We have demonstrated how combining chemoinformatics and bioinformatics for T. cruzi drug discovery can bring interesting in vivo active molecules to light that may have been overlooked.
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Spatial and Temporal Patterns in Preterm Birth in the United States
In order to help generate new research hypotheses, this study explored spatial and temporal patterns of preterm birth in a large, total-population dataset.
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Multi-step Hydrothermal Liquefaction (HTL) of Algae with Nutrient Recycling
A presentation of SRI research to meet the need of a thermochemical process that allows economic conversion of wet biomass to liquid fuels.
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Characterization of Batracylin-Induced Renal and Bladder Toxicity in Rats
To further investigate batracylin’s mechanism of toxicity, studies were conducted in Fischer 344 rats. Once daily oral administration of 16 or 32 mg/kg batracylin to rats for 4 days caused overt toxicity.