SRI International
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Thermospheric Temperatures Above Poker Flat, Alaska, During the Stratospheric Warming Event of January and February 2009
We report observations of neutral and ion temperatures at approximately 240 km altitude above Poker Flat, Alaska, taken during the stratospheric warming event of January and February 2009.
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Diffusion Tensor Imaging in Aging and Age-Related Neurodegenerative Disorders
This chapter reviews evidence for changes in normal aging as the context for establishing abnormalities marking neurological and psychiatric conditions…
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Sound Generator Structure for Low-Elastic Electroactive Polymer
We propose a sound generator structure that provides a mechanical bias with the EAP without an external device and efficiently uses transformation of the EAP to drive the diaphragm.
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Ubiquitin Accumulation in Autophagy-Deficient Mice Is Dependent on the Nrf2-Mediated Stress Response Pathway: a Potential Role for Protein Aggregation in Autophagic Substrate Selection
We show that tissue-specific disruption of the essential autophagy genes Atg5 and Atg7 leads to the accumulation of all detectable Ub–Ub topologies, arguing against the hypothesis that any particular Ub linkage serves as a specific autophagy signal.
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EcoCyc: a Comprehensive Database of Escherichia Coli Biology
Recent improvements to the EcoCyc Web interface include combined gene/protein pages and a Regulation Summary Diagram displaying a graphical overview of all known regulatory inputs to gene expression and protein activity.
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The Rational Design of a Novel Potent Analogue of the 5′-AMP-Activated Protein Kinase Inhibitor Compound C with Improved Selectivity and Cellular Activity
We have designed and synthesized analogues of compound C, a non-specific inhibitor of 5′-AMP-activated protein kinase (AMPK), using a computational fragment-based drug design (FBDD) approach.
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Discovery of the FeO orange bands in the terrestrial night airglow spectrum obtained with OSIRIS on the Odin spacecraft
An unidentified pseudo-continuum in the 600 nm region is observed in the upper mesosphere with the limb-scanning OSIRIS imaging spectrograph on-board the Odin spacecraft.
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From Handheld Collaborative Tool to Effective Classroom Module: Embedding CSCL in a Broader Design Framework
The field of Computer Supported Collaborative Learning (CSCL) includes designers who emphasize effectiveness, measured via experiments, as well as designers who emphasize context and conduct qualitative research on teaching and learning practices.
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Preonset Time Sequence of Auroral Substorms: Coordinated Observations By All-Sky Imagers, Satellites, and Radars
We show that longitudinally narrow flow bursts in the nightside polar cap can precede poleward boundary intensifications that are followed by equatorward moving north-south arcs.
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The Faraday Filter-Based Spectrometer for Observing Sodium Nightglow and Studying Atomic and Molecular Oxygen Associated with the Sodium Chemistry in the Mesopause Region
This paper describes the operational principles, design and field testing of a new, compact, Faraday filter-based spectrometer to measure the D2 (589.158 nm) to D1 (589.756 nm) intensity ratio of the sodium nightglow.
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Inherited Polymorphisms in the RNA-Mediated Interference Machinery Affect MicroRNA Expression and Lung Cancer Survival
Single-nucleotide polymorphisms (SNPs) in genes involved in miR biogenesis may affect miR expression in lung tissue and be associated with lung carcinogenesis and progression.
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Tubulin-binding dibenz[c,e]oxepines as colchinol analogues for targeting tumour vasculature
Various methoxy- and hydroxy-substituted dibenz[c,e]oxepines were prepared via the copper(I)-induced coupling of ether-tethered arylstannanes …