Biomedical sciences publications
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The Impact of Alcoholism on Sleep Evoked Delta Frequency Responses
The KC incidence and amplitude were negatively impacted in alcoholic men and women with exacerbation of the normal aging effects, particularly over frontal scalp regions.
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Dopamine and Opioid Gene Variants Are Associated with Increased Smoking Reward and Reinforcement Owing to Negative Mood
We explored associations of gene variants in the dopamine, opioid, and serotonin pathways with smoking reward (‘liking’) and reinforcement (latency to first puff and total puffs) as a function of negative mood…
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Zebrafish Chemical Screening Reveals an Inhibitor of Dusp6 That Expands Cardiac Cell Lineages
The dual-specificity phosphatase 6 (Dusp6) functions as a feedback regulator of fibroblast growth factor (FGF) signaling to limit the activity of extracellular signal–regulated kinases (ERKs) 1 and 2.
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Application of Subsecond Spiral Chemical Shift Imaging to Real-Time Multislice Metabolic Imaging of the Rat in Vivo After Injection of Hyperpolarized 13C1-Pyruvate
We report on the development of an ultrafast, multislice, spiral chemical shift imaging sequence, with subsecond acquisition time, achieved on a clinical MR scanner.
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Interleukin 17 Production Among Patients with American Cutaneous Leishmaniasis
We show that lymphocytes obtained from patients with mucosal leishmaniasis and cutaneous leishmaniasis produce higher levels of IL‐17 than do lymphocytes obtained from uninfected control subjects (P
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Cellular and Genetic Mechanisms Involved in the Generation of Protective and Pathogenic Immune Responses in Human Chagas Disease
Perhaps one of the most intriguing aspects of human Chagas disease is the complex network of events that underlie the generation of protective versus pathogenic immune responses during the chronic…
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In Vivo Measurement of Ethanol Metabolism in the Rat Liver Using Magnetic Resonance Spectroscopy of Hyperpolarized [1-13C]Pyruvate
Pyruvate is a readily polarizable substrate that has been the subject of numerous magnetic resonance spectroscopy (MRS) studies of in vivo metabolism.
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Organizational Drawing Strategy Enhances Visuospatial Memory in Alcoholism: a 3-Year Follow-Up Study
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Gray Matter Recovery and Its Relationship to Changes in Sleep Evoked Responses After a 12 Month Abstinence in Long-Term Alcoholics
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In Vivo Neurochemical Evidence for Alcohol Binge Induced Neural Compromise and Recovery in Alcohol-Preferring Rats
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Association of Sociodemographic, Lifestyle, and Health Factors with Sleep Quality and Daytime Sleepiness in Women: Findings from the 2007 National Sleep Foundation “Sleep in America Poll”
To investigate factors associated with poor sleep quality and daytime sleepiness in women living in the United States.
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Dopamine Genes and Nicotine Dependence in Treatment-Seeking and Community Smokers
We utilized a cohort of treatment-seeking white cigarette smokers to rank candidate gene single nucleotide polymorphisms associated with the Fagerström Test for Nicotine Dependence.