Biomedical sciences publications
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Social epidemiology of Fitbit daily steps in early adolescence
Our objective was to examine differences in device-based step metrics, including daily step count by sociodemographic factors among a diverse sample of 10-to-14-year-old adolescents in the US.
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The mystery of gamma-hydoxybutyrate efficacy in narcolepsy type 1
Over 40 years have elapsed since the original description of the effects of sodium gamma-hydroxybutyrate (GHB) on sleep [1] and the subsequent description of GHB as an effective treatment for…
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Bedtime screen use behaviors and sleep outcomes: Findings from the Adolescent Brain Cognitive Development (ABCD) Study
We aim to determine associations between bedtime screen time behaviors and sleep outcomes in a national study of early adolescents.
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Circadian Disruption and Mental Health: The Chronotherapeutic Potential of Microbiome-Based and Dietary Strategies
Here, we provide an overview of the link between circadian disruption and mental illness.
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Effects of emerging alcohol use on developmental trajectories of functional sleep measures in adolescents
We tracked developmental changes in polysomnographic (PSG) and electroencephalographic (EEG) sleep measures and their relationship with emergent alcohol use in adolescents considering confounding effects (e.g., cannabis use).
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Association of Demographic and Socioeconomic Indicators With the Use of Wearable Devices Among Children
We examined whether demographic and socioeconomic indicators are associated with willingness to join a wearable device study and adherence to wearable data collection in children.
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Emergence of terpene chemical communication in insects: Evolutionary recruitment of isoprenoid metabolism
We present the first structural and mechanistic model for the evolutionary emergence of TPS function in insects. Through identifying key mechanistic differences between IDS and TPS enzymes, we hypothesize that…
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Effects of the COVID-19 pandemic on screen time and sleep in early adolescents
This study examined changes in sleep habits and recreational screen time (social media, video gaming), and their relationship, before and across the first year of the pandemic in adolescents in…
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Genetically engineered pair of cells for serological testing and its application for SARS-CoV-2
We have developed a serology test platform for identifying individuals with prior exposure to specific viral infections and provide data to help reduce public health risks.
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The progression of radiation injury in a Wistar rat model of partial body irradiation with ∼5% bone marrow shielding
Our purpose is to describe the dose response relationship and natural history of radiation injury in the Wistar rat and its suitability for use in medical countermeasures (MCM) testing.
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Good Sleep is a Mood Buffer for Young Women During Menses
We sought to elucidate the interaction between sleep and mood considering menstrual cycle phase in 72 healthy young women with natural, regular menstrual cycles and without menstrual-associated disorders.
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Activation of the nociceptin/orphanin-FQ receptor promotes NREM sleep and EEG slow wave activity
In the present study, we systematically evaluated the efficacy of two NOPR agonists, Ro64-6198 and SR16835, on sleep/wake in rats, mice, and Cynomolgus macaques.