Biomedical sciences publications
-
Pharmacogenetic Smoking Cessation Intervention in a Health Care Setting: A Pilot Feasibility Study
We conducted a multiphased, mixed-methods feasibility study with current smokers to develop and evaluate a patient-centered, theoretically grounded personalized medicine treatment protocol.
-
Are Women Who Smoke at Higher Risk for Lung Cancer Than Men Who Smoke?
We tested sex-smoking interaction in association with lung cancer risk within a population-based case-control study, the Environment and Genetics in Lung Cancer Etiology (EAGLE) Study (Lombardy, Italy, 2002–2005).
-
Evaluation of IL17A Expression and of IL17A, IL17F and IL23R Gene Polymorphisms in Brazilian Individuals with Periodontitis
The aim of present study was to evaluate the expression of IL17A and occurrence of the IL17A (rs2275913), IL17F (rs763780) and IL23R (rs11209026) gene polymorphisms in different clinical forms or…
-
Circadian Rhythm Disorders: Does Sex Matter?
There are sex-related differences in circadian rhythms with women having shorter intrinsic periods and earlier phase of both temperature and melatonin rhythms relative to men.
-
Sex Differences in Sleep
There are sex differences in sleep behavior with women reporting more sleep problems and a poorer sleep quality than men across a wide age range.
-
Discovery of a Splicing Regulator Required for Cell Cycle Progression
Here we describe a new G1 mutant from an ancient family of apicomplexan protozoans. Toxoplasma gondii temperature-sensitive mutant 12-109C6 conditionally arrests in the G1 phase due to a single point mutation in…
-
Cytotoxic Monacolin Analogs from Monascus Purpureus-Fermented Rice
Two new monacolin analogs, monacolins O (1) and P (2), along with three known analogs, have been isolated from the ethanolic extract of Monascus purpureus-fermented rice.
-
Incorrect ICBM-DTI-81 Atlas Orientation and White Matter Labels
Unfortunately, in our work using this atlas, we have encountered several substantial problems in terms of (a) correctness of spatial orientation and (b) correctness of white matter tract labels.
-
Characterization of a Diffusible Signaling Factor from Xylella Fastidiosa
We describe here the isolation and characterization of an X. fastidiosa DSF (XfDSF) as 2(Z)-tetradecenoic acid. This compound was isolated both from recombinant Erwinia herbicola expressing X. fastidiosa rpfF and…
-
The Tissint Martian Meteorite as Evidence for the Largest Impact Excavation
Here we show that the Tissint meteorite, a 2011 meteorite fall, contains virtually all the high-pressure phases (seven minerals and two mineral glasses) that have been reported in isolated occurrences…
-
A Mechanism of Rapidly Reversible Cerebral Ventricular Enlargement Independent of Tissue Atrophy
Here, multimodal imaging, incorporating structural MRI, MRS, and DWI, was used in rats exposed to binge ethanol to provide insight into a mechanism of reversible ventricular enlargement.
-
Understanding the Sleep-Wake Cycle: Sleep, Insomnia, and the Orexin System
Andrew D. Krystal, MD, MS, gathered a panel of experts in the area of the sleep-wake cycle and insomnia to review recent research and advances in understanding, current treatments for…