Biomedical sciences publications
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Association of the DRD2 Gene Taq1A Polymorphism and Smoking Behavior: a Meta-Analysis and New Data
Our a priori hypothesis was that the association of the DRD2 Taq1A polymorphism with smoking behavior would be more prominent in females than males.
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Discrepancies Between Laboratory Shock Experiments on Minerals and Natural Events
It has become increasingly clear that the pressure "calibrations" based on shock effects observed in these laboratory shock recovery experiments are inconsistent with interpretations based on static high-pressure data.
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Dopamine Transporters: Chemistry, Biology, and Pharmacology
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Neuroimaging of the Wernicke-Korsakoff Syndrome
Presented is the neuroradiological signature of acute Wernicke's encephalopathy (WE), derived from different types of magnetic resonance imaging (MRI) sequences.
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Opioidergic Projections to Sleep-Active Neurons in the Ventrolateral Preoptic Nucleus
We hypothesized that the influence of opiates on sleep may be mediated, at least in part, by the ventrolateral preoptic nucleus (VLPO), a key cell group for producing behavioral sleep.
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Global-Local Interference Is Related to Callosal Compromise in Alcoholism: a Behavior-DTI Association Study
We used a global–local paradigm to assess component processes of visuospatial ability and MR diffusion tensor imaging (DTI) to examine whether alcoholism-related microstructural degradation of the corpus callosum contributes to…
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Adenosinergic and Dopaminergic Signaling as Targets for Wake-Promoting Therapeutics: Insights from Mouse Genetic Models
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Evoked K-Complex Amplitude Is a Sensitive Marker of Adult Brain Aging
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Correlation of Population Parameters Leading to Power Differences in Association Studies with Population Stratification
We implemented a genetic model for population-based association studies with stratified samples and evaluated the impact on power with different genetic scenarios.
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New Developments in Sleep Research: Molecular Genetics, Gene Expression, and Systems Neurobiology
This mini-symposium review highlights some recent developments at the gene, molecular, cellular, and systems levels that have advanced this field.
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Rapid Alterations in Cortical Protein Profiles Underlie Spontaneous Sleep and Wake Bouts
Preliminary microarray analyses show that changes in behavioral state influence regional mRNA profiles; however, the impact of sleep on protein signatures is virtually unexplored. In these studies, cortical protein profiles…
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Variants in Nicotinic Receptors and Risk for Nicotine Dependence
The purpose of this study was to replicate these findings in an independent data set and more thoroughly investigate the role of genetic variation in the cluster of physically linked…