Author: Fiona C Baker
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Associations between mesolimbic connectivity, and alcohol use from adolescence to adulthood
We examined the associations between alcohol use and ventral tegmental area resting-state functional connectivity to subcortical structures in 796 participants across 9 waves of longitudinal data from the National Consortium on Alcohol and Neurodevelopment in Adolescence.
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Resting-state fMRI activation is associated with phenotypic features of autism in early adolescence
In this study, we aimed to explore if activation in brain regions of the default mode network (DMN), specifically the medial prefrontal cortex (MPC), posterior cingulate cortex (PCC), superior temporal sulcus (STS), inferior frontal gyrus (IFG), angular gyrus (AG), and the temporoparietal junction (TPJ), during resting-state functional magnetic resonance imaging (rs-fMRI) is associated with possible…
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Menstruation Problems and Sleep Interactions: Implications for the Mental Health of Adolescent Females
Internalizing symptoms are associated with menstrual cycle characteristics and menstrual pain in female adolescents, especially in those with shorter sleep and later bedtimes. The relationship between the menstrual cycle, sleep, and psychophysiology needs to be integrated in healthcare practice to promote well-being and resilience in young female adolescents.
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Menstrual Cycle Variations in Wearable-Detected Finger Temperature and Heart Rate, But Not in Sleep Metrics, in Young and Midlife Individuals
We use wearable and diary-based data to investigate menstrual phase and age effects on finger temperature, sleep, heart rate (HR), physical activity, physical symptoms, and mood.
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A Longitudinal Study of the Relationship Between Alcohol-Related Blackouts and Attenuated Structural Brain Development
Alcohol-related blackouts (ARBs) are common in adolescents and emerging adults. ARBs may also be indicative of persistent, alcohol-related neurocognitive changes. This study explored ARBs as a predictor of altered structural brain development and associated cognitive correlates
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Metadata-conditioned generative models to synthesize anatomically-plausible 3D brain MRIs
To generate high-quality T1-weighted MRIs relevant for neuroscience discovery, we present a two-stage Diffusion Probabilistic Model (called BrainSynth) to synthesize high-resolution MRIs conditionally-dependent on metadata (such as age and sex). We then propose a novel procedure to assess the quality of BrainSynth according to how well its synthetic MRIs capture macrostructural properties of brain regions…
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Biological sex and BMI influence the longitudinal evolution of adolescent and young adult MRI-visible perivascular spaces
This study assesses the temporal evolution of MRI-visible perivascular spaces (MV-PVS) volume in adolescents and young adults, and secondarily evaluates the relationship between MV-PVS, age, sex, and body mass index (BMI).
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Using Wearable Skin Temperature Data to Advance Tracking and Characterization of the Menstrual Cycle in a Real-World Setting
Here, we show that the menstrual skin temperature variation is better represented by a model of oscillation, the cosinor, than by a biphasic square wave model.
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Multi-dimensional predictors of first drinking initiation and regular drinking onset in adolescence: A prospective longitudinal study.
Early adolescent drinking onset is linked to myriad negative consequences. Using the National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA) baseline to year 8 data, this study (1) leveraged best subsets selection and Cox Proportional Hazards regressions to identify the most robust predictors of adolescent first and regular drinking onset, and (2) examined the…
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Researching COVID to enhance recovery (RECOVER) pediatric study protocol: Rationale, objectives and design
We describe the protocol for the Pediatric Observational Cohort Study of the NIH’s REsearching COVID to Enhance Recovery (RECOVER) Initiative. RECOVER-Pediatrics is an observational meta-cohort study of caregiver-child pairs (birth through 17 years) and young adults (18 through 25 years), recruited from more than 100 sites across the US.
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Sleep, brain systems, and persistent stress in early adolescents during COVID-19: Insights from the ABCD study
Here, we analyzed clusters of perceived stress levels across the pandemic and determined developmentally relevant pre-pandemic risk factors in brain structure and sleep of persistently high stress during the first year of the COVID-19 pandemic.
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Identification and characterization of screen use trajectories from late childhood to adolescence in a US-population based cohort study
This study will identify and characterize the subgroups of adolescents sharing similar trajectories of screen use from childhood to adolescence.