Author: SRI International
-
Nociceptin/Orphanin FQ Inhibition with SB612111 Ameliorates Dextran Sodium Sulfate-Induced Colitis
In this study, we asked whether the small molecule N/OFQ antagonist (−)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol (SB612111) would inhibit the development of dextran sodium sulfate-induced colitis in C57BL/6 mice.
-
Smoking and Genetic Risk Variation Across Populations of European, Asian, and African American Ancestry–a Meta-Analysis of Chromosome 15q25
We demonstrate association between smoking quantity and markers in the chromosome 15q25 region across all three populations, and narrow the region of association.
-
Synthesis of a 35S-Labeled Dinucleoside Phosphorothioate Prodrug, an Orally Bioavailable Anti-HBV Agent
The 35S-labeled, dinucleoside phosphorothioate 1, an orally available agent against hepatitis B virus, was prepared in eight steps with high specific activity and radiochemical purity.
-
Semiotics and the order of acquisition of deictics in L1 French: A corpus-based study
This study examined the acquisition of deixis in French children from the age of 18-32 months. Emphasis was put on the use of demonstrative pronouns, tense and aspect and the order of acquisition in respect to semiotic categories.
-
Characterizing disability in Head Start programs: Not so clearcut
This study used the Head Start Family and Child Experiences Survey data to identify subgroups of children meeting three different criteria for having a disability or developmental delay.
-
Socio-semantic conversational information access
We develop an innovative approach to delivering relevant information using a combination of socio-semantic search and filtering approaches.
-
Thermodynamic principles in social collaborations
A thermodynamic framework is presented to characterize the evolution of efficiency, order, and quality in social content production systems, and this framework is applied to the analysis of Wikipedia.
-
Atomic layer dielectric deposition for flexible organic transistors
We will discuss our low temperature (150C) Al2O3 growth process by plasma assisted-ALD compared to the thermal process on flexible plastic substrates.
-
Inkjet printed organic circuits for addressing non-volatile memory
At Palo Alto Research Center (PARC), organic complementary circuits have been demonstrated by inkjet printing.
-
Mass production of flexible printed temperature sensors
In this report we describe a material set and method for the fabrication of all-printed thermistors on flexible substrates.
-
Opto-fluidic detection system enabling sophisticated point-of-care diagnostics
We have demonstrated and prototyped a new optical detection approach that delivers high signal-to-noise discrimination without complex optics, expensive detectors or bulky excitation sources.
-
Heightened Awareness in Insomnia
… investigate the possibility of hyperarousal in insomnia leading to the possibility of conscious awareness occurring in the context of what we have traditionally viewed to be EEG evidence of NREM sleep.