Author: SRI International
-
Design of Short Linear Peptides That Show Hydrogen Bonding Constraints in Water
Using a combination of an aromatic amino acid, a homoserine side chain, and a d-amino acid, a series of linear tetrapeptides were designed that adopt an “Hse turn” in water.
-
Stimulation of Lateral Hypothalamic Glutamate and Acetylcholine Efflux By Nicotine: Implications for Mechanisms of Nicotine-Induced Activation of Orexin Neurons
Here, we used in vivo microdialysis to determine the effect of acute systemic or local nicotine on glutamate, acetylcholine, and GABA efflux in the LH/PFA of rats.
-
Datasets for Inquiry in Geoscience: A Design Model
This article describes the results of a proof of concept project, Data Sets for Inquiry in Geoscience (DIGS), funded by the National Science Foundation.
-
Design Pattern On Model Use In Interdependence Among Living Systems (Large-Scale Assessment Technical Report 13)
The report outlines the key elements of the design pattern, describes the design pattern development process, and illustrates with examples how the design pattern supports storyboard and item design for interactive science assessments.
-
Meeting Student Challenges to Innovative Instruction with Improved Assessment Techniques
Presentation of an R&D project focused on the assessment of project-based learning involving community college instructors, and engagement in some of the reflection activities that helped instructors identify and measure the skills taught in innovative instruction. Presented at Innovations 2010.
-
Assessing Systems Thinking and Complexity in Science
This technical report provides support for designing tasks that assess systems thinking, in the form of a design pattern.
-
Automatic disfluency removal for improving spoken language translation
We examine the impact of disfluencies from broadcast conversation data on our hierarchical phrase-based SMT system and implement automatic disfluency removal approaches for cleansing the MT input.
-
Comparing the contributions of context and prosody in text-independent dialog act recognition
We propose a framework for employing both speech/non-speech-based (“contextual”) features and prosodic features, and apply it to DA segmentation and classification in multiparty meetings.
-
Daytime Sleepiness, Psychomotor Performance, Waking Eeg Spectra and Evoked Potentials in Women with Severe Premenstrual Syndrome
We assessed daytime sleepiness using objective and subjective measures in women with severe premenstrual syndrome (PMS) compared with women without significant premenstrual symptoms.
-
Increase in Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) Levels and Inhibition of MMP-2 Activity in a Metastatic Breast Cancer Cell Line by an Anti-Invasive Small Molecule SR13179
We report that a novel small molecule synthetic flavanoid SR13179, which inhibits the invasion of a highly metastatic human breast cancer cell line MCF-10CA1a through Matrigel, significantly increases protein and mRNA levels of TIMP-2 in a time- and dose-dependent manner.
-
Scaffolding knowledge communities in the classroom: New opportunities in the Web 2.0 era
This chapter reports two studies that used a wiki to deliver a new curriculum model that blends scripted inquiry activities with collaborative knowledge construction in secondary school biology.
-
Speaker Adaptation of Language and Prosodic Models for Automatic Dialog Act Segmentation of Speech
This study explores speaker-specific modeling for the task of automatic segmentation of speech into dialog acts (DAs), using a linear combination of speaker-dependent and speaker-independent language and prosodic models.