Biomedical sciences publications
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Independent Contributions of Cortical Gray Matter, Aging, Sex and Alcoholism to K-Complex Amplitude Evoked During Sleep
The amplitude of the N550 component derived from the averaged evoked K-complex decreases with normal aging and with alcoholism. The study was designed to determine whether these declines are related…
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Recommendations for the Validation of Flow Cytometric Testing During Drug Development: I Instrumentation
This paper presents a consensus methodological approach that the authors have used successfully to ensure data integrity in flow cytometric studies conducted during drug development.
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Universal Opioid Receptor Ligands – Buprenorphine and Related Orvinols
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Functional and Structural Connectivity and Executive Control in Chronic Alcoholism: a Combined DTI and fMRI Study
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Neurological assessments after treatment with the antimalarial beta-arteether in neonatal and adult rats
This study shows that repeated treatment with clinically relevant doses of βAE causes motor deficits associated with brainstem damage in rodents and suggests that repeated treatment with βAE in children…
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Partial Occupancy of the Glycine Transporter Type 1 in Monkey By Rg1678 Leads to Efficacy in a Model of Prefrontal Cortical Function
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Pharm GKB Summary: Dopamine Receptor D2
Dopamine is a catecholamine neurotransmitter and controls a variety of functions including cognition, emotion, locomotor activity, food intake, and endocrine system regulation in the central nervous system.
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Electrophysiological Evidence of Enhanced Performance Monitoring in Recently Abstinent Alcoholic Men
The objective of this paper is to identify electrophysiological mechanisms of such compensation that would be required to resolve response conflict.
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Neuropeptide B Induces Slow Wave Sleep in Mice
These results suggest that NPB induced physiological SWS through GPR7 and that NPB and GPR7 may have a role in modulating the occurrence of sleep and wakefulness.
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Self-Reported Depressive Symptoms Are Associated with Cognitive Compromise and Poorer Life Functioning in Alcoholism, Hiv and Their Comorbidity
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Sleep-Active Cells in the Cerebral Cortex and Their Role in Slow-Wave Activity
We recently identified neurons in the cerebral cortex that become activated during sleep episodes with high slow-wave activity (SWA).
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Aggressive and Chronic Periodontitis Correlate with Distinct Cellular Sources of Key Immunoregulatory Cytokines
We aimed to investigate the expression of adhesion molecules and the source of proinflammatory and anti-inflammatory cytokines in circulating mononuclear cells from patients with CP and AP.