Biomedical sciences publications
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Effect of Resveratrol on 17 Beta-Estradiol Sulfation By Human Hepatic and Jejunal S9 and Recombinant Sulfotransferase 1E1
Abstract The purpose of this study was to investigate the sulfation of resveratrol (3,5,4′-trihydroxystilbene) and its potential to exhibit drug-drug interactions via sulfation. The possible interaction of resveratrol with 17β-estradiol…
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Frontal Callosal Integrity Predicts Cognitive Interference Compromise in Hiv-Infected Individuals Comorbid for Alcoholism
Diffusion tensor imaging was used to study the combined effects of HIV-infection and alcoholism (ALC) on corpus callosum (CC) integrity in relation to processes of attentional allocation and conflict resolution…
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Volume Reconstruction By Inverse Interpolation: Application to Interleaved MR Motion Correction
We introduce in this work a novel algorithm for volume reconstruction from data acquired on an irregular grid, e.g., from multiple co-registered images.
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Differential Expression of Clock-Related Genes in the Cerebral Cortex of Inbred Mouse Strains in Response to Sleep Deprivation
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Selective 5HT2A and 5HT6 Receptor Antagonists Promote Sleep in Rats
Serotonin (5-HT) has long been implicated in the control of sleep and wakefulness. This study evaluated the hypnotic efficacy of the 5-HT6 antagonist RO4368554 (RO) and the 5-HT2A receptor antagonist MDL100907 (MDL)…
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Preclinical Development of Neuropeptide Therapeutics and Diagnostics
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The Use of a Nasal Resistance Valve to Treat Sleep Disordered Breathing
The present pilot study tests the hypothesis that the application of expiratory resistance via a nasal valve device would improve breathing during sleep in subjects with OSA and in primary…
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Disruption of Top-Down and Bottom-Up Processes in Alcoholics: a Functional Magnetic Resonance Imaging Study
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Genetic and Environmental Influences on Nicotine Pharmacokinetic and Pharmacodynamic Phenotypes
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A Mouse Model for Familial Advanced Sleep Phase Syndrome
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Low Striatal Glutamate Levels Underlie Cognitive Decline in the Elderly: Evidence from in Vivo Molecular Spectroscopy
Here, we used a spectroscopic protocol, optimized for Glu detection, to examine the effect of age in 3 brain regions targeted by cortical efferents—the striatum, cerebellum, and pons—and to test…
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Who is to Blame if Snoring Becomes a Problem?