Bioinformatics publications

Group contribution methods are frequently used for estimating physical properties of compounds from their molecular structures. An algorithm for estimating Gibbs energies of formation through group contribution methods has been…

We describe a novel approach for predicting the function of a protein from its amino-acid sequence.

This article provides an overview of the DB-interoperation problem, and offers several solutions. It discusses how links are used in molecular biology DBs, and describes the potential stumbling blocks when…

We describe the design and implementation of visual presentations that closely mimic those found in the biology literature, and employ a frame knowledge representation system (FRS) called HyperTHEO to manage…

The EcoCyc graphical user interface allows scientists to query and explore the EcoCyc database using visualization tools such as genomic-map browsers and automatic layouts of metabolic pathways.

We propose a network protocol whereby a database administrator can provide information about changes to the identifiers of objects in their database via Internet, to allow other databases to maintain…

We present a methodology for predicting the metabolic pathways of an organism from its genomic sequence.

We have developed a Web server tool, written in Common Lisp, that allows existing graphical user interface applications written using the Common Lisp Interface Manager (CLIM) to hook easily into…

We describe the design and implementation of a storage subsystem that submerges a database management system (DBMS) within a knowledge representation system.

We have developed a Web server tool, written in Common Lisp, that allows any existing graphical user interface application written using the Common Lisp Interface Manager (CLIM) to hook easily…

The Generic Frame Protocol (GFP) is an application program interface for accessing knowledge bases stored in frame knowledge representation systems (FRSs).