Biomedical sciences publications
-
The Association between Postload Plasma Glucose Levels and 38-Year Mortality Risk of Coronary Heart Disease: The Prospective NHLBI Twin Study
We aimed to evaluate whether the association between postload plasma glucose levels (ppGlucose) and long-term risk of mortality from coronary heart disease was independent of or attributable to genes and…
-
Potential Reporting Bias in fMRI Studies of the Brain
Functional magnetic resonance imaging (fMRI) studies have reported multiple activation foci associated with a variety of conditions, stimuli or tasks.
-
Carbon-14 Labeling of K777
The antitrypanosomal agent K777•HCl was labeled with carbon-14 to support absorption, distribution, metabolism, and excretion studies of this potential new drug for the treatment of Chagas disease.
-
First Measurement of the BO B2Σ+ Radiative Lifetime by Laser-Induced Fluorescence Via the B2Σ+–X2Σ+ Transition
Observation of the temporal evolution of the fluorescence following laser excitation of boron monoxide molecules to the B 2Σ+ state is used to extract the radiative lifetime and collisional removal rate constant with…
-
Longitudinal Analysis of the Electroencephalogram and Sleep Phenotype in the R6/2 Mouse Model of Huntington’s Disease
We conducted a longitudinal characterization of sleep/wake and electroencephalographic activity in the R6/2 mouse model of Huntington’s disease to determine whether analogous electroencephalographic ‘signatures’ could be identified early in disease…
-
Curcumin Regulates Colon Cancer by Inhibiting P-Glycoprotein in Cancerous Colon Perfusion Rat Model
In the present study curcumin inhibitory action on p-glycoprotein increased permeability of irinotecan, so in the colon cancer it would be beneficial if curcumin used as add on therapy.
-
Designing Bifunctional Nop Receptor-Mu Opioid Receptor Ligands from Nop Receptor-Selective Scaffolds. Part I
We report here our forays into the structure–activity relationships for discovering ‘bifunctional’ NOP–mu opioid receptor (MOP) ligands, starting from our NOP-selective scaffolds.
-
Non-Clinical Safety Evaluation of Xoma 3AB, a Novel Triple Antibody Drug Product Targeting Botulinum Toxin Type a, in Sprague-Dawley Rats
-
Beta-Carotene Biosynthesis in Probiotic Bacteria
To increase vitamin A coverage in malnourished children, we propose to engineer a probiotic bacterium that will produce β-carotene in the intestine, which will be metabolized to vitamin A.
-
Relationship between Cardiovascular Resting State and Visual Attention
We investigated the relationship between blood pressure, resting heart rate and heart rate variability (HRV) and performance in a visuospatial attention task comparing normotensive and hypotensive young adults.
-
Evoked Responses During Sleep in Young Heavy Drinkers
-
Decision-Making and Brain Structural Substrates in Alcoholism, Hiv Infection, and Their Comorbidity