Biomedical sciences publications
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Comparison of a New Cobinamide-Based Method to a Standard Laboratory Method for Measuring Cyanide in Human Blood
The authors developed and validated a method to quantify cyanide based on the high binding affinity of the vitamin B12 analog, cobinamide, for cyanide and a major spectral change observed…
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The Association between Postload Plasma Glucose Levels and 38-Year Mortality Risk of Coronary Heart Disease: The Prospective NHLBI Twin Study
We aimed to evaluate whether the association between postload plasma glucose levels (ppGlucose) and long-term risk of mortality from coronary heart disease was independent of or attributable to genes and…
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Potential Reporting Bias in fMRI Studies of the Brain
Functional magnetic resonance imaging (fMRI) studies have reported multiple activation foci associated with a variety of conditions, stimuli or tasks.
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Carbon-14 Labeling of K777
The antitrypanosomal agent K777•HCl was labeled with carbon-14 to support absorption, distribution, metabolism, and excretion studies of this potential new drug for the treatment of Chagas disease.
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First Measurement of the BO B2Σ+ Radiative Lifetime by Laser-Induced Fluorescence Via the B2Σ+–X2Σ+ Transition
Observation of the temporal evolution of the fluorescence following laser excitation of boron monoxide molecules to the B 2Σ+ state is used to extract the radiative lifetime and collisional removal rate constant with…
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Longitudinal Analysis of the Electroencephalogram and Sleep Phenotype in the R6/2 Mouse Model of Huntington’s Disease
We conducted a longitudinal characterization of sleep/wake and electroencephalographic activity in the R6/2 mouse model of Huntington’s disease to determine whether analogous electroencephalographic ‘signatures’ could be identified early in disease…
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Cardiac Autonomic Activity During Sleep in Recently Sober Alcoholics
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Longitudinal Changes in Sleep EEG and Brain Structure in Adolescence
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Wernicke-Korsakoff Syndrome: A Nutritional Alcohol-Related Brain Disorder
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Antileishmanial Activity of Natural Product-Like Naphthoquinones
The antileishmanial activity of compounds inspired by naphthoquinone secondary metabolites from Bignoniaceae is presented.
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Structure and Function of Parkin E3 Ubiquitin Ligase Reveals Aspects of RING and HECT Ligases
Here we present the 1.58 Å structure of Parkin-R0RBR, revealing the fold architecture for the four RING domains, and several unpredicted interfaces.
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Interleukin-6 Gene Polymorphism (−174 G/C) is Associated with Toxoplasmic Retinochoroiditis
This study suggests that the genotypes related with a lower production of IL-6 may be associated with the occurrence of TR.