Biomedical sciences publications
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T2 Relaxation Times of 13C Metabolites in a Rat Hepatocellular Carcinoma Model Measured in Vivo Using 13C-MRS of Hyperpolarized [1-13C]Pyruvate
Following hyperpolarized [1-13C]pyruvate injections, pyruvate and its metabolic products, alanine and lactate, were observed in the liver of five rats with hepatocellular carcinoma and five healthy control rats.
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Hyperpolarized (13)C MRSI for Therapeutic Response Monitoring of Prostate Cancer to Radiotherapy
In this technique, the transient fate of pyr and its downstream metabolites lactate (lac), alanine, and bicarbonate is measured with 13C Magnetic Resonance Spectroscopy Imaging (MRSI) following an injection of hyperpolarized…
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In Situ Chemical Analyses By Underwater Mass Spectrometry
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MicroRNA Expression Differentiates Histology and Predicts Survival of Lung Cancer
We investigated whether microRNA (miR) expression profiles can differentiate histologic subtypes and predict survival for non–small cell lung cancer.
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Cytokine Measurements in a Mouse Vaginal Irritation Model for the Safety Evaluation of Microbicides
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Shewanella knowledgebase: integration of the experimental data and computational predictions suggests a biological role for transcription of intergenic regions
The Shewanella knowledgebase was established in 2005 to provide a framework for integrated genome-based studies on Shewanella ecophysiology.
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Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized By Abnormalities in PDGFRA, IDH1, EGFR, and NF1
We provide a framework that unifies transcriptomic and genomic dimensions for GBM molecular stratification with important implications for future studies.
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Binge Ethanol Treatment Is Insufficient to Elevate Cytokine Levels Measured in Rat Blood, Liver, and Brain
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Synthesis and Tissue Distribution Studies of Acyloxyalkyl Prodrug Derivative of an Anti-HBV Dinucleotide
The preferential distribution of the dinucleotide 1 and its prodrug 2 into liver may be attributed to the presence of nucleoside phosphorothioate backbone because phosphorothioate oligonucleotides also reveal a similar…
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The Metal-Responsive Transcription Factor-1 Protein Is Elevated in Human Tumors
In the present study, we investigated MTF-1 protein expression in human tissues by specific immunostaining of both normal and tumor tissue samples.
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Disrupted Frontocerebellar Networks in Alcoholics Revealed By Resting State Functional Connectivity Imaging
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Disruption of Bottom-Up Processes in Alcoholics: Examination with Visuoperceptual Testing and Quantitative Fiber Tracking